Biology
When an enzyme is involved in a catabolic reaction A. its active site binds the substrates and changes shape, stressing the bond, lowering the activation energy, and breaking the bond. B. its active site binds the substrates and changes shape, bringing them close together, lowering the activation energy, and creating a bond. C. its active site binds the substrates and changes shape, stressing the bond, increasing the activation energy, and breaking the bond. D. its active site binds the substrates and changes shape, creating a bond by increasing the activation energy. E. None of the above.