Julia had a sibling who died because of a genetic disease as an infant. Before having children, she and her husband Tobias get genetic testing and counseling. They are unlucky.

For the GAA gene, Julia has one normal allele and one totally non-functional allele. Tobias has one normal allele and one totally non-functional allele.

If any of their offspring test positive for Pompe disease, when are symptoms likely to develop (remember, both parents have one non-functioning allele, 0%GAA)?

1.) Before the age of nine months

2.) Anytime during adolescence up through middle adulthood.

Answers

Answer 1
I'm thinking that it is 2
Answer 2

The right answer is A.

It turns out that this family possesses in their gene the infantile form of Pompe disease, so the disease will appear early in the offspring.

Pompe disease is caused by a deficiency of lysosomal acid α-glucosidase resulting from mutations in the GAA gene. The clinical spectrum ranges from a rapidly fatal multisystem disorder (classical, beginning before 1 year) to less severe myopathy in adults.


Related Questions

Light energy from the sun is converted by plants into _____. electricity chemical energy leaves mechanical energy

Answers

Light  energy   from    sunlight   is  converted  by  plant  into  chemical  energy.This  chemical  energy  is  temporarily   stored   in ATP  and  the   energy  carrier  molecules  that is  NADPH.      This  involve  a   process  known  as  photosynthesis  whereby  radiation  energy  from   sunlight   is   converted to  chemical  energy .Photosynthesis  involve  a  series    of  steps   and  uses  solar  energy,water  and   carbon  dioxide  to  produce  organic  compounds

Answer:

chemical energy

Explanation:

In starfish, pink boy color(P) is dominant to orange(p) , and thick eyebrows(T) are dominant over thin(t) ones. Patrick , who is heterozygous for body color but purebred for thick eyebrows , has met Patti , who is recessive for both traits.


What's patti's phenotype?

Is it possible for the new couple to have offspring that resmeble their mother? explain?

Answers

Phenotype is the actual description of the traits based on the genotype. The genotype of Patti is pptt both recessive so both recessive traits are expressed. So her phenotype is orange-colored with thin eyebrows

To answer your question 2, we can use a Punnett Square:
Genotype of the parents:
PpTT and pptt

        PT       PT       pT        pT
pt   PpTt   PpTt     ppTt     ppTt
pt   PpTt   PpTt     ppTt     ppTt
pt   PpTt   PpTt     ppTt     ppTt
pt   PpTt   PpTt     ppTt     ppTt

Remember that dominant traits are always expressed. Based on the Punnett square that there is always a dominant T trait in each, which means that the offsprings of Patrick and Patti would have thick eyebrows.  The mother Patti has thin eyebrows. So the answer is no in terms of eyebrows.

When it comes to skin color, for the offsprings to be the same as their mother, the genotype of the skin color should be both pp, and there are 8 out of 16 squares, so there is a 50% chance that they will have orange skin.

If the condition is that they should have both thin eyebrows and orange skin, then the answer is it would be impossible.  

these group of cells represent different ___

a. organelles that carry out different functions
b. tissues in which similar cells function together
c. organs that help to carry out a specific life activity
d. systems that are responsible for a specific life activity

thanks!! xoxo

Answers

In the image, these groups of cells perform the same function. The correct answer is "tissues in which similar cells function together". For instance, the cells from the bladder lining, collectively, have the ability to transform from stratified to squamous epithelium therefore accommodating the storage of urine. 

Answer:

b. tissues in which similar cells function together

Explanation:

I got it right on my test.

If an experiment starts with 6 bacteria cells and ends with 96 bacteria cells, how many generations did the cells go through?

Answers

The bacterial cells went through 4 generations.
6 --> 12 --> 24 --> 48 --> 96
Final answer:

In order to calculate the number of bacteria generations, you use logarithms. Taking the log base 2 of the final number of bacteria divided by the initial number gives approximately 4 generations.

Explanation:

The generational growth of bacteria cells is typically exponential, doubling with each generation. Since we're starting with 6 cells and ending up with 96, we need to figure out how many times 6 needs to be doubled to get 96. This can be calculated by using the formula of logarithm base 2. Firstly, divide 96 by 6 to get approximately 16 then, calculating the base 2 logarithm of 16, gives us about 4. So the cells went through about 4 generations.

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The ends of DNA molecules form telomeres that help keep the ends of chromosomes from sticking to each other. Why might this be especially important in germ cells, which go through meiosis and make haploid gametes?

Answers

if the ends of two chromosomes stick together, the chromosomes will not separate correctly during meiosis. one of the resulting gametes will have an extra chromosome, and the other will be missing a chromosome

The telomeres which keep the ends of chromosomes from sticking to each

other is important because it helps to prevent mutation and death  of

offspring.

Telomeres are referred to as the ends of the chromosome. They prevent

sticking together of the homologous chromosomes during the process of

separation in meiosis.

If the telomere is absent and sticking together happens then one of the

resulting gametes will have extra chromosome with a corresponding

deficiency in the chromosome of the other thereby resulting in lower

reproductive rate,  mutation and death

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The genetic makeup of a trait is represented by two letters. what do these letters represent?

Answers

The two alleles, one inherited from each parent

All of the following are stops on the pathway of taste signals except __________.



A.

taste receptors


B.

the prefrontal cortex


C.

cranial nerves


D.

the thalamus

Answers

B. The prefrontal cortex is used to plan complex cognitive behavior, personality expresison, and moderate social behavior.

Answer :All the following are the stops on the pathway of taste signals except The prefontal cortex.

The taste receptors, cranial nerves and the thalamus are the terms associated with the taste. The taste receptors detects the various kinds of tastes. The cranial nerves and the thalamus also helps in the detection of taste and sensory receptors.

The prefontal cortex is the region of brain  that is associated with the social behavior, decision making, personality.





Which of these substances is commonly derived from animals for medical purposes?
A. Morphine
B. Aspirin
C. Estrogen
D. Paclitaxel

Answers

Answer:

Estrogen

Explanation:

Estrogen are hormones that increase the development and maintenance of female characteristics in the human body. Estrogen is involved in the development of a range of health issues.

Final answer:

An C. Estrogen is commonly derived from animals for medical purposes.

Explanation:

Estrogen, a group of hormones primarily associated with the development and regulation of female secondary se-xual characteristics and the menstrual cycle, can be sourced for medical purposes from various origins, including animals. One common source is pregnant mare urine (PMU), where conjugated equine estrogens are extracted for hormone replacement therapy.

Additionally, some pharmaceuticals may use synthetic or plant-based estrogens. However, there are ethical and sustainability concerns related to animal-derived hormones. Today, there is a growing shift towards the use of synthetic or plant-based estrogens due to their availability, consistent quality, and reduced impact on animal welfare and the environment.

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What is the correct chromosomal condition at prometaphase of mitosis?

Answers

Final answer:

In prometaphase of mitosis, chromosomes compact and become visually distinguishable, the nuclear envelope breaks down, and the mitotic spindle's microtubules attach to the kinetochores on the chromosomes.

Explanation:

During the prometaphase of mitosis, the chromosomal condition is that each chromosome compacts and becomes visually distinguishable under a light microscope. The nuclear envelope begins to break down, and the chromosomes, composed of two sister chromatids, free in the cytoplasm of the cell. Moreover, the microtubules from each centrosome, constituents of the mitotic spindle, attach to a specific protein structure on the centromere of each chromosome called a kinetochore. This ensures that each daughter cell receives an equal distribution of chromosomes during the ensuing mitotic phase, metaphase.

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Breathing through the nose rather than the mouth is advantageous because

Answers

air is humidified on inhalation, water loss is reduced on exhalation, heat loss is reduced on exhalation, air is warmed.. all are correct. 
Question:- Breathing through the nose rather than the mouth is advantageous because

Answer:- The nose warms, humidifies, and filters inhaled air. The majority of the nasal cavity is lined with: pseudostratified ciliated columnar epithelium.

What do all carbonate minerals have in common?

Answers

they are on the periodic table

Should commercial fruit farmers be allowed to use ethylene to accelerate the ripening of fruit for the market? Why or Why not?

Answers

The answer is: NO

Accelerated ripening of fruits lowers the quality of the fruits because it circumvents the  natural process of ripening. In some cases of accelerated ripening, one finds a premature fruits looking ripe. In other cases, it causes ununiform ripening and also causes  hastened senescence reducing shelf life.

The commercial fruit farmers should not be allowed to use ethylene.

Though ethylene is a natural growth regulator in the plant, if it is not applied in limited  quantity it produces adverse effects such as overly ripened fruits, yellowing of green fruits and fruit becoming excessive soft and loose to pre maturity. It leads to chlorophyll destruction and also inhibits vegetative tissue. It also inhibits auxin transport, flower development, shoot and root growth.

Trees do not move like birds do but they are living things. why

Answers

Trees aren't made biologically the same way as birds. For this same reasons this is why humans don't "fly". Yes, we have developed technologies to create an atmosphere forgoing the fact that we don't have wings or 'webbed' limbs to help us fight the force of gravity while in the air. This is why trees cannot fly, because they are born that way biologically for a purpose, to convert carbon dioxide to oxygen.

The main energy resource used by industrialized countries is

Answers

Fossil fuels. Industrialized countries use coal and gas to run their cars, heat their homes, and provide electricity.

Why does this particular case interest Holmes? A. Holmes feels sorry for Mr. Wilson. B. The case presents a unique course of events. C. The case involves red-headed men. D. Holmes is looking for a new hobby

Answers

The correct answer is B. The case presents a unique course of events

The type of line recognized by the brain and eyes but is not actually present.

Answers

Implied line

Hope I helped! ♡

Property Expected from Muscle Fibers..?

Answers

it would be the first one
Final answer:

Muscle fibers are complex multicellular units equipped with several components that enable their functional properties, most importantly muscle contraction. These include the sarcolemma (plasma membrane), sarcoplasm (cytoplasm), sarcomeres (functional unit), and several other structures and proteins. There are also different types of muscle fibers that use different metabolic methods to generate ATP, the energy for muscle contraction.

Explanation:

Skeletal muscle fibers are long, multinucleated cells contained within a plasma membrane, the sarcolemma. The cytoplasm of the cell is referred to as sarcoplasm, which along with the specialized smooth endoplasmic reticulum or sarcoplasmic reticulum plays an important role in the property of muscle contraction through the release and retrieval of calcium ions. The functional unit of a muscle fiber is the sarcomere, an organized arrangement of actin and myosin filaments that, through a series of steps, shorten to produce movement.

The number of sarcomeres and myofibrils within a muscle fiber, which can be influenced by factors such as hormones and stress, can result in hypertrophy, increasing the mass of a muscle, or, if muscle use is decreased, atrophy, wherein the muscle mass decreases. The three types of skeletal muscle fibers, slow oxidative, fast oxidative, and fast glycolytic, each use a different metabolic method to generate ATP, the energy for muscle contraction.

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Which statements describe the characteristics of an individual protein? Check all that apply.
It is specific to one biochemical reaction.
It increases the activation energy needed for a reaction.
It can catalyze many different reactions.
It increases the rate of a biochemical reaction.
It slows down the rate of a biochemical reaction.

Answers

It is specific to one biochemical reaction.

It increases the rate of a biochemical reaction.


The characterstics of individual protein are:-

it is specific to one biochemical reactionit increases the rate of a biochemical reactionWhat are proteins?

Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acids.

What is biochemical reaction?

It is the transformation of one molecule to a different molecule inside a cell.

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The vascular pressure that declines from roughly 35 mm hg to about 18 mm hg is the

Answers

The correct answer is "capillary hydrostatic pressure". 

The 35 mmHg is the pressure in the arterioles. This pressure will go down as there is an increase in resistance to blood flow in the arterioles before going to the capillaries. 18 mmHg capillary hydrostatic pressure is roughly the average of the arterial pressure and the venous pressure.

what is represented by the sequence below?
a. a feedback mechanism in multicellular organisms
b. differentiation of organic molecules
c. the disruption of cellular communication
d. an immune response by cells of the pancreas

thanks! xoxo

Answers

Think it’s a) the feedback system :)

a. a feedback mechanism in multicellular organisms

The nurse is assessing a client who has syndrome of inappropriate antidiuretic hormone (siadh). which finding in the client is consistent with the diagnosis?

Answers

There are choices for this question namely: 

1. Decreased serum sodium level 
2. Decreased serum creatinine level 
3. Increased hematocrit 
4. Increased blood urea nitrogen (BUN) level

The correct answer is "decreased serum sodium level". Syndrome of inappropriate antidiuretic hormone or SIADH is a disorder of the posterior pituitary gland wherein there is an abnormal increase in the secretion of antidiuretic hormone. As a result, there will be a decrease in water secretion in the renal distal tubules. Eventually, this will lead to a decrease in serum sodium level as a result of dilution. 

Answer:Retention of water

Explanation: SIADH is manifested in the form of retention of free water. This is bc of excessive secretion of vasopressin causing reabsorption of water in renal tubes.

Where are cardiac pacemakers usually positioned during​ implantation?

Answers

I believe they are positioned Beneath one of the clavicles. Pacemaker is a small device that's placed in the chest or abdomen to help control abnormal heart rhythms. This device uses electrical pulses to prompt the heart to beat at a normal rate. Pacemakers are used to treat arrhythmias. Arrhythmias are problems with the rate or rhythm of heartbeat.

Habitat destruction is the leading cause for declining populations of species on our planet. Due to human development, industry, and forestry, humans are destroying the habitat of many species at an alarming rate. Consider the bald eagle. The bald eagle population was threatened in the late 60s and early 70s. Thanks to an aggressive bald eagle protection program, bald eagle numbers in the wild have soared as seen in the population graph above. The bald eagle's population very nearly reached extinction. Why did the bald eagle's declining population make it more vulnerable to extinction? A) As populations decline, reproduction stops B) As populations decline, less resources are available C) As populations decline, there is less genetic diversity D) As populations decline, birds migrate farther away from other populations

Answers

The answer is C) As populations decline, there is less genetic diversity. This is called the 'founder effect'. With limited numbers of individuals in a population, it is more likely that highly-related individuals will mate. This will result in recessive and deleterious genes being manifested in the phenotype. Consider that higher organisms are diploid: they contain two complete sets of chromosomes, one from each parent. Within each chromosome, some alleles will be dominant while others will be recessive, i.e., for the recessive alleles to be manifested in the phenotype, both have to be recessive, whereas for the dominant allele, only one of the alleles has to be dominant for the allele to manifest in the phenotype. With lower genetic diversity, a higher proportion of individuals will have chromosomes containing both recessive alleles, which may manifest as lowered fitness and genetic disorders.   

 C)  As populations decline, there is less genetic diversity

As populations decline, there is less genetic diversity The bald eagle's population reached alarmingly low numbers due to habitat loss and with low populations, there is not as much genetic variability. With fewer variations, a species survival is difficult to overcome without conservation efforts.

~USATestprep~

How does the structure of a red blood cell relate to its function?

Answers

The main function of a red blood cell transport the oxygen throughout the body to other cells. It has haemagoblin that allow the binding of oxygen. It’s biconcave shape maximizes the surface area to increase efficiency of oxygen absorption and allows it to “squeeze” through narrow vessels and can enter thinnest capillaries through the body. Red blood cells don’t have a nucleus, so it increases the oxygen capacity.
Help this helps! ;)

Due to its biconcave shape, red blood cells have the ability to deliver the amount of oxygen to various organs and tissues of the body of an individual.

What do you mean by Red blood cells?

Red blood cells may be defined as a type of blood cell that is made in the bone marrow and found in the blood which contains hemoglobin.

Red blood cells do not have a nucleus in their structure and contain hemoglobin which increases the affinity of oxygen to bind with it and transport this bound oxygen to the whole body through the transport of bounded oxygen with hemoglobin particles.

Therefore, the function of RBCs with respect to their structure is described above.

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A student is studying a process in which a diploid cell becomes haploid. Which of these shows the CORRECT mathematical model for the process if Nnew is the number of chromosomes in the haploid cell and Nold is the number of chromosomes in the diploid cell?

Answers

I don't see any models, but when a cell turns from Diploid to Haploid, its number of chromosomes is halved or divided by 2.
So if Nnew is: 23 or n = 23 , then Nold will be: 46 or 2n = 46

Answer:

N new = Nold /2.

Explanation:

Meiosis may be defined as the process of cell division in which a single parent cells divides into the four daughter cells. The meiosis occurs generally in the gametic cells.  

Here, the diploid cells becoming the haploid cells, it means the chromosome number is reduced to half in the new cell. This can be represented mathematically as  N new = Nold /2..

Thus, the answer is N new = Nold /2.

If aden- means gland, what word could mean a tumor of the sebaceous glands?

Answers

Final answer:

The term for a tumor of the sebaceous glands combining 'aden-' for gland and '-oma' for tumor is 'sebaceous adenoma', which is a benign growth originating from the oil-producing sebaceous glands.

Explanation:

If the term "aden-" refers to a gland and we are discussing a tumor of the sebaceous glands, the medical term for such a tumor would often include the suffix "-oma", which refers to a tumor. Thus, the word that could describe a tumor of the sebaceous glands is "sebaceous adenoma". A sebaceous adenoma is a benign tumor that arises from the sebaceous glands which are responsible for producing sebum.

Sebum is the oily substance that helps to lubricate and protect the skin and hair. While sebaceous adenomas are usually not serious and often do not require treatment, they could potentially indicate an underlying condition if they are multiple or irregular.

A specimen is 0.2 mm long. Calculate the length of its image if it magnified by 1000 times.

Answers

200 cause 0.2 times 1000 is 200
magnification is equal to the ratio of image height(H) to the object height(h)
Therefore,

m=H/h

1000=H/0.2

H = 1000 * 0.2

So,
Image height (H) = 200 mm

Which human activity does not affect the Earth system? (1) disposing of toxic wastes (2) converting solar energy (3) clearing land for farming (4)
burning natural gas and coal

Answers

Converting Solar Energy
I think the answer is converting solar energy

Endotherms normally have larger brains than ectotherms. What connection do you see between the two characteristics?

Answers

endotherms have larger brains bc they live in more environments all over the world and need a bigger brain to basically help them analyze behavior of other animals such as prey and predator. also bc they have larger lungs they need to be able to take in oxygen and such 

Answer:

The energy required by brain cells are 10 times more than the normal body cells. Ectotherms are cold-blooded animals so they need heat energy from the sun to remain active but endotherms can regulate their body temperature due to large brain.

So the increase in temperature helps in increase in the size of the brain in endothermic animals. The basal metabolic rate in large endotherm is 10 times less than the basal metabolic rate of large ectotherms which supports the large brain in endothermic animals.

The endothermic brain contains more glial cells than the ectothermic brain this is also the reason that the brain of endotherms is larger than the brains of ectotherms.

Based upon the mechanics of mantle convection, which feature will most likely be formed at the blue arrow, and through which mechanism?

Answers

the correct answer is A) an island arc will be formed by ridge push

Other Questions
The psychosocial approach primarily focuses on ___________. the impact of poverty on development the emergence of identity over the life course longevity of individuals cultural values in isolation Read this excerpt from a short story. Liam navigated the busy park, scanning the crowd for his friends. They had agreed to meet at the water slide, and soon the towering steps came into view. He spotted Rachel and Marco by the inner tubes, and soon the three were racing to the top of the slide. There were over a hundred wooden stairs to climb, but the friends usually climbed them without pause. This time, however, their progress was slowed by a surprising mid-day crowd. Spiraling up the stairs were dozens of eager park patrons, each gripping a slippery tube. Liam shook his head and told his friends they would need a little more patience than usual waiting for their favorite view from the top. What complication is introduced in the excerpt? Marco is unable to locate his friends in the busy park. The slides wooden stairs are in need of repair. Marco and his friends have to wait in a long line. Park patrons are not following the rules of the slide. Small, oddly shaped bones that fill gaps between bones of the skull are called What do the amino acids phe, tyr and trp have in common? You are selling items from a catalog for a school fundraiser. Select two inequalities that you can use to find the range of sales that will earn you at least $40 and at most $50. Then find the range of sales. Let x represent the amount of sales (in dollars). Marge cut 16 pieces of tape for mounting pictures on poster board. Each piece of tape was 3/8 inch long. How much tape did Marge use? Choose the correct future tense form of the verb in parentheses. Nosotros (hacer) el trabajo. har harsharemos harn Subtract 1.05 from a certain number. Multiply the difference by 0.8, add 2.84 to the product then divide the sum by 0.01 and get 700. What is the number? the gray is a sidewalk and the turquoise is grass. Both are squares. What is the area of the sidewalk? A) 4 ft2 B) 36 ft2 C) 44 ft2 D) 48 ft2 On the attendance worksheet, in cell l5, enter an if function to determine if the percentage in cell k5 is greater than or equal to the goal in cell h18. the function should return the text goal met if true and review if false. set the reference to cell h18 as an absolute reference A used bookstore will trade 2 of its books foe of yours, If Val brings in 18 books to trade,how many books can she get from the store What gene are we going to attempt to introduce into our bacterial strain? PLEASE HELP ME SOLVE WILL MARK AS BRAINLIEST IF ANSWERED CORRECTLY AMND SERIOUSLY k/2+1-1k=-2k A window washer cleaned 38 windows in 2 hours. At this rate, how many windows did he clean in 7 hours? What is the primary goal of managing diabetes? what is the process of determining a specific age of an object. How did women's roles in society change during the 1920s? The sum of two numbers is 46 and the difference is 14. What are the numbers? 3, 12, 48, 192, 768, . . .This sequence has aA.] common difference of 4B.] common ratio of 4C.] common difference of [tex] \frac{1}{4}[/tex]D.] common ratio of [tex] \frac{1}{4}[/tex] what was the primary target of Peter the Great's westernization policies