What is the difference between a virus and bacteria
Birth control pills are a popular form of contraception for women. How do birth control pills prevent pregnancy?
A.by covering the cervix and blocking sperm from entering the uterus
B.by blocking the Fallopian tubes and keeping the eggs from reaching the uterus
C.by introducing female hormones that prevent the ovaries from releasing eggs
A nurse is caring for a client with the diagnosis of right ventricular failure. which condition unrelated to cardiac disease is the major cause of right ventricular failure?
Chris begins to sweat when he works out. the sweating that occurs
How does the age structure affect population growth short answer?
Which post disaster phase is generally characterized by optimism due to an infusion of resources?
He human gene egfr located on chromosome 7 is a proto-oncogene that codes for a growth factor cell surface receptor. the binding of growth factors to this receptor can lead to cell proliferation. hypothesize what potential impact a mutated egfr allele will have on a cell. give one possible impact and explain your answer
A mutated EGFR gene may cause the up-regulation of the growth factor receptors. This causes an abnormally high levels growth factor response to occur even when growth factors have not bound the receptor causing the epidermal cells to proliferate. This unregulated growth causes cancer such as adenocarcinoma.
The mutated EGFR allele leads to development of cancer.
Further Explanation:
Proto-oncogenes are the genes that induces normal cells to become cancerous if they are mutated which is dominant in nature.
The mutated proto-oncogene becomes oncogene when mutated. Most of the time proto-oncogene encodes proteins which stimulates the cell to divide, inhibit cell differentiation and prevents cell death and these processes is crucial for normal development and maintenance of organs. But oncogenes shows higher cell division, decreased cell differentiation and cell death inhibition which is the characteristics of cancer cell.
EGFR or Epidermal Growth Factor Receptor functions in regulating the epithelial tissue developmental process and homeostasis. In cancer cells EGFR is inappropriately activated in the cancer cell due to point mutations or transcriptional upregulation. EGFR has also been marked as the biomarker of resistance in tumors.
EGFR are involved in canonical EGFR signaling pathway which is ligand and kinase-dependent.
When there is absence of stimulation, the EGFR is normally found to be in auto-inhibited, incompetent state in plasma membrane. Binding of ligand allows the receptor dimerization which further leads to EGFR kinase activation.
EGFR signaling can be disrupted due to EGFR gene amplification or mutations. Mostly the mutations occurs in glioblastoma and lung cancer. These genetic lesion is accompanied by increase in EGFR ligand production.in certain cases genetic changes determines the abnormal trafficking of EGFR that leads to enhanced signaling and tumor development.
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Answer Details:
Grade: College biology
Subject: Biology
Chapter: Cancer biology
Keywords:
Proto-oncogenes , genes, normal cells, cancerous, dominant, oncogene, proteins, cell, tissues, organs, EGFR, Epidermal Growth Factor Receptor, homeostasis, resistance, ligand, plasma membrane, signaling, tumor.
The nurse is educating a patient regarding breathing techniques. what technique should the nurse avoid in a patient with chronic obstructive pulmonary disease (copd) who has marked hyperinflation?
Horses and donkeys can interbreed. The offspring that develops called a mule, is sterile and unable to produce its own offspring. Would these be considered the same or different species?
blue jays and robins do not interbreed. assuming that blue jays and robins share the same habitat, describe the possible conditions that keep these bird reproductively isolated. explain your answer.
Why does heating up a protein cause it to lose function?
Membranes in living cells, including those in humans, are characterized by a separation of charge across the membrane. effectively, the membranes are thus charged capacitors with important functions related to the potential difference across the membrane. is energy required to separate these charges in living membranes and, if so, is its source the metabolization of food energy or some other source?
Yes, energy is required to separate the charges. Mostly, the inner of the cell membrane is negatively charged compared to the outside. When the cell becomes depolarized, ions, especially, Sodium ions, are pumped out by active transportation to restore resting potential. Active transport requires energy from ATP powered by food metabolism.
Final answer:
Yes, energy is required to separate charges across the cell membrane, and it is derived from the metabolization of food. This process is crucial for establishing a membrane potential necessary for many cellular functions, including signal transmission in nerve and muscle cells.
Explanation:
Energy and Charge Separation in Cell Membranes
Cell membranes in living organisms, including humans, function similarly to capacitors as they exhibit a separation of charge across their structure. This charge separation, or membrane potential, is fundamentally important for many cellular processes, including the conduction of electrical signals in nerve and muscle cells. The membrane potential is typically in the range of 70 to 90 mV, creating an immense electric field due to the thinness of the membrane.
The formation and maintenance of this potential difference do require energy. In biological systems, this energy is derived primarily from the metabolization of food, which provides the ATP necessary for energy-dependent processes such as active transport. Notably, the sodium-potassium pump, one of the critical active transporters, utilises this energy to maintain concentration gradients of sodium and potassium ions across the cell membrane, thereby contributing to the separation of charges.
Indeed, it is estimated that a significant portion of a cell's energy expenditure, about 25%, is dedicated to creating and sustaining the membrane potential. This underscores the vital role that the managed separation of charges plays in cellular homeostasis and function.
A placebo is a substance that is unlikely to affect the dependent variable true or false ?
Answer:
true
Explanation:
apex
A nurse is teaching a class to parents about keeping medications and household cleaning supplies out of the reach of toddlers. the nurse explains that this is necessary because toddlers:
Stimuli that increase the probability of a response they follow by removing an unwanted stimulus are called _____.
What factor would account for a strong synovial joint?
A.small reinforcing ligaments
B.low muscle tone
C.synovial fluid
D.the deepest articular surface
Small reinforcing ligaments are the factor contributing to the strength of a synovial joint. They provide stability and prevent dislocation, hence making the joint stronger. Other factors like low muscle tone, synovial fluid, and the deepest articular surface do not directly contribute to the joint's strength.
Explanation:The factor that would account for a strong synovial joint is essentially the small reinforcing ligaments. Ligaments are tough, flexible tissues that connect bones or cartilage and also hold joints together. A synovial joint fortified with small reinforcing ligaments will tend to be stronger as they provide stability and help to prevent dislocation.
Options B, low muscle tone, and D, the deepest articular surface, do not directly contribute to the strength of a synovial joint. Synovial fluid, option C, certainly plays a role in the joint's ability to function smoothly by acting as a lubricant, but it does not inherently make the joint stronger.
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What does the Nucleus contain? What role do its contents play in the cell?
The nucleus significantly contains the genetic material of living organisms. It is responsible for encoding genetic characteristics within the individual. It is also known as the "controlling center of the cell."
What is Nucleus?The nucleus was first discovered by Robert Brown. It possesses a double-layer covering called a nuclear membrane. It contains pores that allow the transfer of material. It also contains chromosomes that are only visible during the time of cell division.
The nucleus contains nucleolus which is rich in protein and RNA. It is also known as the factory of ribosomes and is helpful in protein synthesis. Nucleus also helps in the transfer of genetic information from one generation to another.
Therefore, the nucleus significantly contains the genetic material of living organisms.
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Consider the life cycle of a typical frog. Where within the life cycle does fertilization take place? A) A. B) C. C) D. D) E.
Final answer:
Fertilization in the life cycle of a typical frog occurs externally in moist environments. The life cycle consists of a larval stage where the tadpoles live in water, breathing with gills, and a metamorphosis stage where they develop into air-breathing adults.
Explanation:
In the life cycle of a typical frog, fertilization takes place externally. Frogs lay their eggs in moist environments to prevent the eggs from dehydrating, as they lack a hard shell. The life cycle of frogs includes the larval stage, where tadpoles are filter-feeding herbivores, breathing with gills and having a lateral line system. This is followed by metamorphosis into the adult stage, during which the gills and lateral line system are absorbed, limbs develop, and they transition to a carnivorous diet and air-breathing lifestyle with lungs and an eardrum.
Which problem is most directly caused by dumping waste in landfills?
Pollution of undergroundwater
True or false if a plant grows toward the stimulus it shows a negative tropism
False.
A plant growing towards a stimulus is positive tropism.
Which statement describes a species that is at carrying capacity?
what is formed as a waste product in photosynthesis and used as a reactant in respiration.
Emir is taking a premed class where they need to study all of the structures of the body, including the nervous system, respiratory system, and reproductive system. he is taking a class on _____.
Studying the anatomy and physiology of the nervous system.
Explanation:The nervous system is one of the key systems studied in anatomy and physiology courses, including aspects of its structures and functions.
Understanding the nervous system involves anatomical and physiological techniques to explore its complexities at different levels.
Students in this course delve into topics like nervous system cells, sensory systems, motor systems, and more as they learn about the nervous system's role in the human body.
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What is a possible cause of solar prominences?
Answer:
The dense cloud of luminescent ionized gas protruding from the chromosphere of the Sun into the corona is termed as solar prominence. The prominences on certain occasions extend thousands of kilometers above the chromosphere of the Sun. The reasons for the solar prominences are not clear, however, they involve intense magnetic forces.
The prominences differ considerably in shape, size, and motion and are of two prime kinds, that is, quiescent and active. The solar prominences may form over timescales for a day and may prevail in the corona for many weeks or months, and loop hundreds of thousands of miles into space.
Suppose you observed 455 individual cockroaches in the infested apartment after 5 years of exposure to hydramethylnon + glucose bait. if the population had not evolved, how many individuals of each genotype would you expect? round your answers to the nearest whole number. (for help getting started, see hint 1.)
Sexual reproduction has never been observed in which type of fungus
Why is getting accurate numbers for the rate of child abuse so difficult?
The reason that it is hard to obtain accurate number is because many child abuse cases are not reported. Being a child that is growing up in a abusive life may think that it is okay to be hit or to call others name; that’s the main reason why when they grow up as adult they will be also abusive as a person.
The brain operates on two levels. one of these is the _____ level.
Answer:
The two levels are Awareness and Unconsciousness (consciousness)
Explanation:
A brain is an organ of the central nervous system it functions can be found in all vertebrate and invertebrate animals. located close to the visual senses. Gives signals impulses that act as action potentials that act on distant parts of the body. Unconsciousness is the state when the ability to maintain a sense of the environment and the surroundings is essentially lost involving a complete or near-complete lack of response to stimuli. It may also occur as a result of brain hemorrhage or brain hypoxia, severe fatigue and other cause. Where consciousness i.e the awareness is the quite opposite in which the person operates his present state of mind.Dogs have 78 chromosomes in their diploid cells. how many chromosomes are in their haploid cells?
When the complete der ring des nibelungen (the ring of the nibelung) is performed, it lasts about how long?
It is 18 hours long.