Process that leads to increased affinity of antibodies for a protein antigen as a humoral response progresses through somatic mutation of ig genes to selective survival of b cells is called

Answers

Answer 1
The answer is affinity maturation. The process allows the B cells and humoral response to be more effective against the same antigen with every secondary infections.
Affinity maturation is the result of somatic hypermutation of the genes that code for variable region (Fab) of immunoglobulins. This increases the variability of the B cell receptors hence increased probability for affinity of Ig to the antigen. The Ig variant that is effective against the antigen will be selected and reproduced by memory B cell during secondary infections.
Answer 2

Answer: Affinity maturation

 Affinity maturation is the process that leads to increased affinity of antibodies for a protein antigen as humoral response progresses. B cell maturation in the germinal center is a result of somatic mutation of immunoglobulin genes, which provide the molecular basis for the selective survival of B cells producing the highest affinity antibodies. These B cells are thought to have a competitive advantage when antigen becomes limiting in germinal centers.

 


Related Questions

What is the evolutionary value of mutations?

Answers

Diversity and emergence of new traits (can be beneficial in some cases). Mutations are part of what drive evolution and allow for that change to take place. 

Mutations are crucial for evolution as they are the primary source of genetic variation. Although most mutations are neutral or harmful, some can be beneficial, leading to better adaptation and evolution. This genetic diversity allows for natural selection and the survival of the fittest.

Mutations are changes to an organism's DNA and are an important driver of diversity in populations. They serve as the ultimate source of genetic variation, which is crucial for evolution. Without them, evolution would not occur.

Most mutations are neutral or harmful, but a small percentage can have beneficial effects, leading to new versions of proteins that enable better adaptation to environmental changes. This genetic diversity allows some individuals to have a survival advantage, leading to natural selection and subsequently, evolution.

For instance, a gene might encode a product with an essential function as well as a potentially useful function for reproductive success. Mutations that enhance these additional functions will persist in the gene pool if they do not overly hinder the gene's primary function. This balance is essential for the flexibility of evolutionary mechanisms.

Which is the best example of a pure substance? a) peanuts b) milk c) gold d) air?

Answers

Correct option is C. Gold is the best example of a pure substance as it is an element composed of a single type of atom. Other examples like peanuts, milk, and air are mixtures. Pure substances have a fixed chemical composition and distinct properties, while mixtures consist of two or more pure substances.

The best example of a pure substance from the options provided is c) gold. Peanuts, milk and air are all mixtures containing more than one substance. Gold, as an element, consists of only one kind of atom and cannot be broken down into a simpler substance by chemical means, making it a pure substance. Let's elaborate on some of the examples given:

Cardboard is a mixture because it is made of various substances such as cellulose fibers, adhesives, and other additives.

Caffeine is considered a pure substance as it has a fixed chemical composition and characteristic properties.

Tin, an element, is a pure substance constituted entirely of one type of atom.

A vitamin tablet is a mixture because it contains a variety of compounds and often includes fillers or binders.

Helium gas is often very pure, especially when used in scientific applications, and is considered a pure substance.

What are 5 Clever Way psychologists have for measuring implicit forms of prejudice?

Answers

To empirically assess implicit prejudices, sub-conscious behavioral patterns, such as eye-blinking within a conversation or other features of body-language, are measured. The results of such indirect measures often allow for a considerably precise prediction of how types of behavior or judgment are influenced.

A scientist observed the formation of hundreds of maggots and many flies on a rotting meat slice exposed to the environment. What most likely formed the maggots?

A. Water vapor present in the surrounding air
B. Eggs of flies in the surroundings
C. Nutrient crystals in the meat
D. Oxygen in the environment

Answers

The correct option is B.
Female flies are the one that are saddle with the responsibility of laying eggs during reproduction. The female usually look for a warm and moist place that have abundance food source for laying the eggs. The eggs laid by by the flies transformed into larva, which is also called maggots and the maggots turn into flies.

eggs of flies in the surroundings is the answer.


How have scientific advancements helped reduce the impact of hazardous events on society?

a. Scientific advancements have led to the ability to detect some hazardous events before they occur, allowing society to plan for them, mitigating their damage. b. Scientific advancements have led to the ability to prevent hazardous events. c. Scientific advancements have led to the ability to detect all hazardous events, preventing damage to society. d. Scientific advancements have not reduced the impact of hazardous events on society.

Answers

a. Scientific advancements have led to the ability to detect some hazardous events before they occur, allowing society to plan for them, mitigating their damage.

Scientific advancements helped reduce the impact of hazardous events on society in various ways. As science progress and study hazardous events, it is possible to be able to predict some of them, this allows society to be prepared, at least in theory, and with the knowledge comes the ability to mitigate them, and avoid suffering, economic costs and even loss of lives to the people that are unluckily involved in those types of events. 

Answer:    

A. Scientific advancements have led to the ability to detect some hazardous events before they occur, allowing society to plan for them, mitigating their damage.

Explanation:

What process do cells use to engulf larger substances, encase them in vesicles, and bring them into the cell?

Answers

i think it is endocytosis

These cancers represent the most common cancers in the United States.
1 lung, bone, prostate
2breast, pancreatic, stomach
3skin, breast, lung
4pancreatic, prostate, lung

Answers

Answer:

The correct answer is 3) skin, breast, and lung.

Explanation:

Being that they are the top 3 common cancers in the US and widespread across the world.

The cancers that represent the most common cancers in the United States is the breast, pancreatic, and stomach. Option B.

What is cancer?

Generally, Cancer is simply defined as a disease in where certain cells in the body grow and spread to diverse parts of the body.

In conclusion,  the most common cancers in the United States is the breast, pancreatic, and stomach as they represent most people having it.

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which material are you most likely to find in the O horizon

Answers

I think the answer to this is Parent Material 

Undecomposed material


Primates are distinguished from other mammals by __________.

Answers

Well primates have opposable thumbs and no tail

Which is an energy conversion that occurs during cellular respiration?

Answers

A) ADP>ATP 

This answer is 100% correct I took the test.

Scientists at Russia’s Vostok Station in eastern Antarctica drilled the longest ice core ever recorded. They compiled this graph using the data collected from the ice core. This plot shows the temperature, carbon dioxide (CO2), and dust levels up to 400,000 years ago. Which statement best summarizes the data in the graph?

Answers

The data supports the fourth choice, that increasing air temperature and CO2 levels correlate with a decrease in dust concentration.

The first choice is unlikely to reflect dust concentration, and is more likely to be for air temperature. The second choice is false, because the dust concentration is more of a decreasing trend. The third choice is not true, as the spikes in air temperature and atmospheric CO2 concentrations seem to occur simultaneously, implying a positive correlation.

Answer:

The answer is D.

Explanation:

most of the insulin manufactured today to treat diabetes is produced by

Answers

It is produced by transformed bacteria.

Is the common iliac vein anterior or posterior to the femoral artery?

Answers

The common iliac vein is posterior to the femoral artery. Attached is an image showing that the common iliac vein is posterior to the femoral artery.

Imagine a root of a cotton plant growing in the upper horizon of an irrigated soil in california's imperial valley. as the root attempts to draw water molecules from this soil what forces (potentials) must it overcome? if this soil were compacted by a heavy vehicle, which of these forces would be most affected?

Answers

A root of a cotton plant must overcome various potential forces such as gravitational forces that pulls water downward, matric forces where there is an adhesion of water molecules from a soil and osmotic forces where attracting water in the presence of large amount of soluble salts in the mixture of soil.

If the soil were compacted by a heavy vehicle, the matric forces would be mostly affected for compaction will result to increase matric forces due to reduced size of pores of the soil making it more difficult to draw water from a solid surface.

 

A cotton plant's root must overcome gravitational, matric, and osmotic potentials to draw water from the soil. Compaction by heavy vehicles primarily affects the matric potential by reducing soil permeability. This could also affect root water uptake by altering the hydraulic gradient and conductivity.

To draw water molecules from the soil, a root of a cotton plant must overcome several forces or potentials, such as gravitational potential, matric potential, and osmotic potential.

Gravitational potential is the force due to gravity pulling on the water. The soil must counteract this to prevent all water from draining away. Matric potential is the soil's adhesion and cohesion forces acting on water, which plants must overcome to uptake water. For osmotic potential, the presence of solutes like salts means plants face more difficulty drawing water into roots. The Imperial Valley's soil, known for salinization, could affect osmotic potential.

If the soil is compacted by a heavy vehicle, the most affected force is the matric potential. Soil compaction reduces pore space, making it harder for roots to access water due to reduced soil permeability. Compaction could also affect the rate of root water uptake due to changes in the hydraulic gradient and soil hydraulic conductivity.

What is the name given to the original finch that diverged in to 15 different species? A. Darwin's finch B. Radiant finch C. Ancestral finch D. First finch

Answers

A. Darwin's Finch was the name given to the original finch that diverged into 15 different species.
The appropriate answer is C. ANCESTRAL FINCH. The study of these birds on the Galapagos island led to Darwin proposing his theory of natural selection. Darwin collect and preserved samples of the finches he observed while on his travels.
He did not observe anything unique about the birds until after he returned home. He focused on the differences in the beaks of the birds. It is then that he started to work on his revolutionary theory.

List the three bacterial species in order of their increasing fastidiousness

Answers

The term fastidiousness refers to the complexity of an organism's nutritional requirements. A fastidious microorganism will only grow if the culture medium provides the necessary nutrients. This table provides the readings on the optical density from bacterial cultures. This reading gives an indication of the concentration of the bacteria in the culture; the higher the concentration of bacteria, the greater scatter of light and the higher value of optical density. Yeast extract broth, nutrient broth and glucose broth are culture media which are enriched with more nutrients. In all these three media, S.mitis had the lowest optical density, meaning the lowest concentration. We can conclude that S.mitis is the most fastidious microorganism of the three. Then comes A.faecalis and the least fastidious of the three is E.coli.

In order of increasing fastidiousness, the list of bacterial species starts with Escherichia coli, followed by Staphylococcus aureus, and ends with Micrococcus luteus, with E. coli being the least demanding and M. luteus the most demanding in terms of growth requirements.

The term fastidiousness in biology refers to the level of nutritional and environmental specificity that bacteria require for growth. To list bacterial species in order of their increasing fastidiousness is to arrange them from the least demanding to the most demanding in terms of the growth conditions they require. Including the bacterial species provided in the question, we can list Escherichia coli (E. coli), Staphylococcus aureus (S. aureus), and Micrococcus luteus based on their typical fastidiousness.

Escherichia coli, a Gram-negative coliform species, is known for its ability to grow in a variety of environments with minimal nutritional requirements, which classifies it as the least fastidious of the three. In contrast, Staphylococcus aureus, a Gram-positive species, is moderately fastidious, requiring more specific nutrients and conditions than E. coli, but still capable of growing in many environments. Lastly, Micrococcus luteus is considered highly fastidious, requiring specific nutrients and conditions not necessary for the growth of the other two species, making it the most fastidious in this list.

Therefore, the bacterial species in order of increasing fastidiousness are:

Escherichia coliStaphylococcus aureusMicrococcus luteus


please tell me the protons neutrons and electrons of americium

Answers

Hello,

Here is your answer:

The proper answer to this question is "p=95, e=95, n=148".

Here is how:

Protons=95
Electrons=95
Neutrons=148

Your answer is 95, 95, 148!

If you need anymore help feel free to ask me!

Hope this helps! 


At high noon, you're laying on the beach. You can feel _____ air coming from _____.

Answers

At high noon, you can feel warm air coming from inland. During noon, especially in spring and summer, the radiation caused by the Sun warms the land surface more compared to the sea surface. This is because heat is directly applied on the land surface compared to the ocean.
feel warm air coming from inland

A particular co-transporter uses the concentration gradient of na+ to move an amino acid into the cell. what immediate effect would raising the extracellular na+ have? it would…
a. increase the amino acid's rate of entry into the cell.
b. block the movement of the amino acid into the cell.
c. block the na+ / k+ pump.
d. speed up the na+ / k+ pump.
e. reverse the direction of the na+ / k+ pump so that it moves na+ and k+ down their concentration gradients.

Answers

Raising the extracellular [Na+] would have the effect of…
a. increase the amino acid's rate of entry into the cell.

State three ways scientists base their identifications of evolutionary relationships.

Answers

Three ways scientists base their identifications of evolutionary relationships are:
1. Does not take genetics into account.
2. Does not consider convergent evolution.
3. Physical similarities does not mean that they are related.

Evlutionary relationships talks about relatedness between organisms, usually this can be shown by a phylogenetic tree through phylogeny. Reconnection and speciation of organisms must be considered in studying relatedness of organisms.

Predict a potential outcome of a mutated MAD protein

Answers

MAD protein are mutants cells and they can be refers to as mitotic arrest deficient. MAD protein act by recruiting the anaphase inhibitor MAD2 to dissociate kinetochores and its essentials from MAD2-CDC20 complex formation in vivo.

However, there mutation will produce defective protein and checkpoint failure by resulting into aneuploidy. Aneuploidy is when a cell finishes the process of mitosis and produces daughter cells with few or too many chromosomes and aneuploidy causes more than 90% of human cancer.

The potential outcome of a mutated MAD protein is development of aneuploidy in daughter cell.

Further Explanation:

The cell cycle is referred as the prearranged flow of steps that include the cellular division as well as cell growth. This cycle form two new daughter cells. The cycle is begins with the interphase. In this phase, mainly the cell replicates and matures its DNA.

The second stage of a cell cycle is the mitosis or M phase. Mitosis is a kind of cell division. In this, parental cells divide into two daughter cells which have the same number of chromosomes as that of the parent cell

MAD protein is a kind of a protein that mainly present in humans and this protein is encoded by MXD1 gene. This protein is mutant cell that is referred as mitotic arrest deficient. This protein has a role in recruiting an inhibitor MAD-2 which is anaphase inhibiter help in dissociating the kinetochores.

Development of any Mutations in the MAD protein can develop a defective protein and malfunction of the checkpoints. The cell ends the cell cycle by the last stage which mitosis. In the presence of mutated MAD protein daughter cell cannot develop properly. Daughter cell can have very low or high number of chromosome and can result in aneuploidy condition. Mainly aneuploidy cell develop or result in cancer cell.

Learn more:

1. Learn more about mitosis https://brainly.com/question/6462270

2. Learn more about the menstrual cycle https://brainly.com/question/723944

3. Learn more about meiosis https://brainly.com/question/94813

Answer Details:

Grade: High School

Subject: Biology

Chapter: Cell Cycle

Keywords:

Cell cycle, parent cell, mitosis, aneuploidy, daughter cell, protein, MAD, mutated protein, encoded, human, checkpoints, cancer cell, daughter cell, chromosome.

Which occurrence would contradict the big bang theory

Answers

can you please give me more detail?

not enough information

The big bang theory states that the universe began approximately 10-20 billion years ago in an expansion of the universe emanating from an extremely compact point. The occurrence of super massive black holes contradict the big bang theory. Super massive black holes are found at the center of galaxies and is what keeps them together. Models do not explain how these would have formed if the big bang occurred the way it was proposed.

A 65 year-old male with a history of chronic glaucoma has progressive optic nerve damage and elevated intraocular pressure. a clear corneal incision is made and viscoelastic material is injected into the anterior chamber over the lens to increase and maintain anterior chamber depth. the endoscope is inserted through the temporal incision to view the nasal ciliary processes, which is coagulated with the endpoint of shrinkage and whitening. the endoscope is moved in an arc, allowing treatment of the processes over an arc of 180° and a second corneal incision is made 90° away and 180° of ciliary processes are destroyed with laser therapy. the surgeon has completed coagulation of 270° of angle. the eye is reformed with balanced salt solution. wounds are checked for leakage and sutures are placed to seal the wound. what cpt® code is reported?

Answers

Glaucoma is a disease involving increased intraocular pressure as well as optic nerve damage leading to progressive loss of vision. The surgery done in the patient is called trabeculectomy which involves incision and repair of the iris and the ciliary body. This corresponds to the CPT code of 66711, under destruction procedures on the iris, ciliary body of the eye.

A particular gene can have 2 forms, called alleles.Which statement best describes the difference between the dominant allele and the recessive allele?
A) only the dominant allele is expressed when the both allele are inherited
B) only recessive allele is expressed when both allele are inherited
C) the recessive allele is expressed only if it moves to a different chromosome
D) the dominant allele can be expressed only if two homologous chromosomes have it

Answers

The correct option to show the simple allele relationship between them would be A. The dominant allele or the preferred DNA sequence is used to make protein more often than the recessive allele, if both are present.
A.............................................

True or false plant cells derive their energy from chlorophyll

Answers

Hello,

Here is your answer:

The proper answer to this question is option A "true".

Here is how:

ChlorophyII is where plants get there energy.

Your answer is A.

If you need anymore help feel free to ask me!

Hope this helps!

Why is it necessary to rinse the inside of erlenmeyer flask with di water periodically?

Answers

Hi there!

It is necessary to rinse the inside of an Erlenmeyer flask with deionized water periodically to wash the flask without adding ions which could affect the titration. 

If you wash an Erlenmeyer flask with regular tap water, you are adding ions, like sodium or chlorine, which could make you miss the equivalence point by only tenths of mL (that's a big difference when titrating). This is why when washing you use deionized water to clean the flask while ensuring that your titration is accurate.

Have a good day!

Which organisms are eukaryotes? sunflower bacteria cow

Answers

Eukaryotes are organisms with a nucleolus like a sunflower and cows. Bacteria is a prokeryote which means it has just a nucleus.

Answer:

sunflower and cow are eukaryotes

Explanation:

A eukaryotic organism is one who have enclosed nucleus ( i.e nucleus is enclosed with in a membrane). However in a prokaryotes the nucleus is exposed. Bacteria’s have exposed nucleus and thus they are prokaryotic organism. Eukaryotic domain includes animals, plants, algae and fungi as its constituent’s members.  

Since sunflower is a plant and cow is an animal, these two lie in the eukaryotic domain of organisms.  

The original pith is still located in the center of the stem (inside the vascular bundles). What type of cells makes up the pith?

Answers

Answer;

Parenchyma cells

Explanation;The pith is a part of the Ground tissue together with the cortex. The cortex is located to the outside and/or around the vascular bundles, while the pith is locate in the center of the stem. Both the cortex and pith are composed mainly of parenchyma cells. On the other hand collenchyma cells give support to the stem and may occur under the epidermis in the cortex.Pith is composed of soft, spongy parenchyma cells, which store and transport nutrients throughout the plant.

In the gene pool of a population with 350 individuals, a fixed allele has a frequency of

Answers

In  the  gene  pool   of  population   with   350   individuals  a   fixed  allele  has   a   frequency   of   1(one).  Fixed  alleles    is  the  alleles  that  is  the  only  variant  that  exist  for  that    gene  in  all  population.The  frequency  of   gene   pool  with  a  population  of   350   is  = 1  since  the    frequency   of    total  alleles  =1
Final answer:

A fixed allele in a population is one where every individual carries the same version of a gene. This means its frequency is 100% in the gene pool, representing complete prevalence in the population's genetic diversity. The study of allele frequency and gene pools is vital in understanding evolution and genetic variation.

Explanation:

The concept of a fixed allele refers to a situation in a genetic makeup where every individual in a population carries the same version (allele) of a gene. In population genetics, the allele frequency, or gene frequency, is the rate at which a specific allele appears within a population. Overall, it's a crucial concept in studying how populations evolve over time. For instance, if an allele provides a survival advantage, it can become more common throughout generations, eventually reaching a point where it's the only version present in the population (a fixed allele).

A gene pool, on the other hand, is the total number of genes of every individual in an interbreeding population. It represents the genetic diversity within a population. So, in a population of 350 individuals, if an allele is fixed, it means that the frequency of that allele is 1 or 100%, as every individual in that population carries that particular allele in their genetic makeup.

An understanding of allele frequency and gene pools is essential to study and understand the process of evolution and genetic variation within a population. Factors like mutation, gene flow, genetic drift, and natural selection all influence the frequency of an allele in a population.

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which are structures of the excretory system? check all that apply. kidney, spleen, bladder, esophagus, ureter, urethra

Answers

The right answer is kidney, bladder, ureter, urethra.

The urinary tract is the device that allows the evacuation of catabolism products from the human body in a liquid form, the urine, and thus ensures the purification of blood and the maintenance of homeostasis within the body. organization. Also, it maintains the blood balance, the volume and the chemical composition of the blood. To do this it eliminates, among other things, the surpluses of certain minerals, called electrolytes, and returns to the blood the substances that are useful for the proper functioning of the organism (reabsorption).

Every day, a human being produces 800 to 2,000 milliliters of urine. The urinary tract is included in the excretory system (as the large intestine and the lungs).

This apparatus is a succession of retro- and subperitoneal organs: the two kidneys, the two ureters, the bladder and the urethra.

Answer:

Kidney, Bladder, Ureter, Urethra.

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