The first randomized, controlled study of an experimental drug versus aspirin for postoperative pain control will enroll 45 subjects in each arm. Which of the following best describes the clinical phase of this study?a. Phase Ib. Phase IIc. Phase III

Answers

Answer 1

Answer:

Phase II

Explanation:

The above question exposes an example of scientific study. This type of study is characterized as a set of basic rules used in the development of an investigation in order to produce scientific knowledge, obtaining the most reliable results possible, either in the production of new knowledge, as well as in the correction and integration of scientific knowledge.  

This type of study encompasses some phases, such as observation, hypothesis formulation, experimentation, interpretation of results, and finally conclusion. In the case of the study shown above, the step outlined in the question is phase II, also known as "hypothesis formulation". Phase II begins shortly after phase I, called observation. Observations must be made precisely and very carefully, down to the last detail.

Phase II is a possible explanation for a given phenomenon and should be tested by a large number of experiments. If the hypothesis is confirmed, it may give rise to laws and theories. In this case, we can confirm that "the randomized controlled trial of a postoperative pain control versus aspirin drug that will record 45 subjects in each arm" is an example of hypothesis testing, so this study refers to phase II.

Answer 2
Final answer:

The study described is a Phase II clinical trial, focused on monitoring the drug's efficacy and side effects in a small patient group.

Explanation:

The clinical phase that best describes the first randomized, controlled study of an experimental drug versus aspirin for postoperative pain control is a Phase II clinical trial. Phase II trials involve a small number of patients, typically between 100 and 300, to determine the drug's efficacy. The subjects are carefully monitored for side effects and the consequences of the drug treatment. This phase prioritizes ensuring that there are no detrimental side effects and that the drug has a positive effect before proceeding to Phase III, where the number of participants increases significantly to between 1,000 and 3,000 patients.


Related Questions

Fetal circulation differs from the circulatory path of the newborn infant. In utero the fetus has a hole connecting the right and left atria of the heart. This allows oxygenated blood to quickly pass to the major organs of the body. What is this hole called?

Answers

Answer:

Foramen ovale

Explanation:

The foramen ovale is a hole that communicates the right side with the left side of the heart. During pregnancy, it is this communication that enables the fetus to receive its mother's oxygenated blood to develop since its lungs still do not function. Soon after birth, there is the natural closure of the foramen ovale. However, in a minority of people this natural closure does not occur and the foramen ovale remains open, ie patent, throughout life.

Corey is trying to cut back on his consumption of caffeinated beverages. He will NOT experience: Please choose the correct answer from the following choices, and then select the submit answer button.

Answers

Answer: Corey will not experience an increase in energy after cutting back on caffeinated beverages.

The correct answer is "increased energy."

Explanation:

After a person stops or cuts back on caffeine consumption, they may suffer from withdrawal symptoms. Caffeine gives people a quick burst of energy for a short amount of time. If the person has been using caffeine as an energy booster, they may suffer from the withdrawal symptom of being tired. Since their body is no longer getting the quick burst of energy, they may become fatigued. They are also likely to suffer from moderate to severe headaches for the first few days.

​ Regarding infant sensory abilities, which of the following statements is FALSE?
a. ​Newborns can discriminate among different tastes and show a preference for sweetness.
b. ​By about four to six months of age, infants show a preference for faces reflecting their own racial characteristics.
c. ​Newborns can recognize a scrambled picture of their mother’s face just as wel

Answers

Answer:

I believe that the best answer to the question: Regarding infant sensory abilities, which of the following statements is FALSE, would be, C: Newborns can recognize a scrambled picture of their mother´s face just as well.

Explanation:

The development of skills, abilities and capacities in children, especially during infancy, is a pretty complex, and unique one. What is known up to this point for sure regarding babies, since birth till they turn about 2 years, is that: they have difficulties in vision, as they cannot see certain features, colors, and after a certain range. They recognize their caregivers, especially their mother, first and foremost through touch and smell, as well as through audition. These characteristics develop as the child´s brain, and body, start also to develop from the moment they are born and they leave babyhood to enter early childhood. But in general, newborns, and up until about 6 to 7 months of age CANNOT recognize faces after a certain distance has been reached from them, and definitely not a scrambled one, even of their mothers. They are more likely to recognize the mother first by her smell, her touch and her voice, than her face. This recognition comes as the baby´s visual capacity enhances. However, they are able to distinguish tastes and that is why they tend to prefer their mother´s milk; because it is sweet to the taste, and they start recognizing racial features, especially skin color, at about six months of age. This is why the answer is C.

A nurse cares for a client with megaloblastic anemia who had a total gastrectomy three years ago. What statement will the nurse include in the client's teaching regarding the condition?
A. "The condition is likely caused by a folate deficiency."
B. "The condition is likely caused by a vitamin B12 deficiency."
C. "The condition causes abnormally rigid red blood cells."
D. "The condition causes abnormally small red blood cells."

Answers

Answer:

The correct answer is B

Explanation:

Vitamin B12 requires intrinsic factor to be absorbed. This factor is secreted by parietal cells of the gastric mucosa. So it is common that patients who have had a gastrectomy develop this type of anemia.

Also Vitamin B12 is key to maturation of erythrocytes (red blood cells) and its deficiency leads to abnormal shapes (particularly more rounded erythrocytes). So options C and D can be rule out.

You have responded to a report of an abrupt collapse of a middle-aged man at a local office building. Your BLS assessment shows the man is unresponsive, not breathing normally, and has no carotid pulse. This condition is most likely caused by and treated with:

a) respiratory arrest; rescue breaths, recovery position
b) secondary cardiac arrest; CPR, effect rescue breaths
c) sudden cardiac arrest; CPR, defibrillation
d) altered mental status; recovery position, monitor breathing

Answers

Answer: Option C

Explanation:

This condition man is due to cardiac arrest and the treatment that could have been done is CPR and then defibrillation.

The cardiac arrest can be defined as the condition by which there is a abrupt loss of heart function who may or may not be diagnosed with heart disease.

It can be fatal if not cured properly and immediately. It can be cured by providing CPR and defibrillation which cure this problem.

hence,the correct answer is option C

Answer:

Sudden cardiac arrest; CPR, defibrillation

Explanation:

Benny enjoys the feelings created by drinking alcohol. However, over the last several years he has noticed that it takes more and more alcohol to create the desired effects. MOST specifically, Benny's experience illustrates the phenomenon of: _________

Answers

Answer: tolerance

Explanation:

Substance tolerance is the condition in which the body craves for more amount of dose of a particular substance so as to experience the desired effect. This can occur in abusers of drugs and alcohol.

Thus this can be said that Benny's experience suggests the phenomena of tolerence of alcohol.

Jan tries to focus on the tip of her pencil as she brings it closer to her. She feels the strain on her eye as she does this. What she is feeling in her eye is due to the process called
a. inhibition.
b. reflection.
c. accommodation.
d. assimilation

Answers

Answer:

I think the answer is D.

Safe Patient Handling Programs implemented by hospitals typically show cost savings over time. A. True B. False

Answers

Hi !

Safe Patient Handling Programs implemented by hospitals typically show cost savings over time.

A. True

Hospitals are doing this Program as it helps them to save cost and free from hassle and injury to the nurses, patience and other hospital personnel.

An adult is swinging a small child by the arms, and the child screams and grabs his left arm. It is determined in the emergency department that the radial head is partially dislocated. What is this partially dislocated radial head documented as?

Answers

Answer: The partially dislocated radial head is documented as a "Subluxation."

Explanation:

Any type of partial dislocation is referred to as a subluxation. This can occur in a joint and even in an organ in the body. It is considered as structural displacement. A simple x-ray can diagnosis when a subluxation occurs. In the case listed above, it was in the shoulder. Symptoms of subluxation are visible swelling, pain in the area, unable to move the joint, and/or numbness and tingling. The subluxation may also be visible by a deformity in the shoulder area. Many times this can be fixed by using a splint, resting and using ice on the dislocated area, and elevating the arm. In some cases, surgery may be necessary, especially, if it occurs in the back.

A partially dislocated radial head in a child is known as a nursemaid's elbow or radial head subluxation, typically treated with a simple manipulation to realign the joint.

The partially dislocated radial head in a child that you've described is documented as a nursemaid's elbow or radial head subluxation. This is a common injury among young children, often resulting from a sudden pull on the extended and pronated arm, as might happen when an adult lifts or swings a child by the arms. The radial head slips partially out of the ligament that holds it in place, causing pain and a refusal to use the arm. Proper diagnosis and treatment usually involve a simple manipulation technique by a healthcare provider to reduce the subluxation and relieve discomfort.

You see a 3-year-old girl in an ambulatory clinic because she has a bad cold. Her mother tells you the girl's problem was caused by her being affected by "mal ojo." What would be the best action?
a) Tell her mother this is not a legitimate illness.b) Explain there is nothing to do for illnesses caused by evil spirits.c) Ask her mother what symptoms her daughter is experiencing.d) Teach her mother that colds are caused by viruses.

Answers

Answer:

d) Teach her mother that colds are caused by viruses.

Final answer:

The best action would be to ask the girl's mother about the symptoms her daughter is experiencing.

Explanation:

The best action would be to choose option c) Ask her mother what symptoms her daughter is experiencing. By asking the mother about the symptoms, the healthcare provider can gather more information about the girl's condition and determine an appropriate course of action. It is important to approach the situation respectfully and gather as much information as possible to provide the best care for the girl.

In the second hour after the client gives birth her uterus is firm, above the level of the umbilicus, and to the right of midline. What is the most appropriate nursing action at this time?

Answers

Final answer:

The proper nursing action when the uterus is firm, above the umbilicus, and to the right of midline post-birth is to assess for and alleviate bladder distention to facilitate uterine involution and reduce the risk of postpartum hemorrhage.

Explanation:

In the second hour after the client gives birth her uterus is firm, above the level of the umbilicus, and to the right of midline. The most appropriate nursing action at this time is to assess the bladder for distention. A uterus that is firm and deviated to one side, especially the right, often indicates a full bladder displacing the uterus. A full bladder can impede the process of involution, where the uterus contracts to return to its pre-pregnancy size, and can increase the risk of postpartum hemorrhage. The nurse should encourage the client to void or, if necessary, consider catheterization to relieve bladder distention, facilitating the uterus to return to midline and promote effective involution.

The question of how someone's personality traits can be explained by unfulfilled wishes and childhood traumas would be of MOST interest to a psychologist working from a(n) _____ perspective.

Answers

Answer:

Psychodynamics

Explanation:

The question of how someone's personality traits can be explained by unfulfilled wishes and childhood traumas would be of MOST interest to a psychologist working from a(n) psychodynamics perspective.

Stanley is 7 years old. His parents are quite concerned about his school progress Although he has begun to learn to read, he reverses some letters when he writes. Based on research, Stanley's school counselor should tell his parents that:
a. brain development can be quite uneven in childhood and as a result, it is
not unusual for children to show poor performance in isolated skills.
b. Stanley almost certainly has a serious learning disorder which requires
immediate intervention.
c. if a child shows normal progress in other reading related skills, like
Stanley does, the child is probably faking the letter reversals in a bid for
attention.
d. Stanley needs glasses.

Answers

I think the answer is A

Rashad is in the hospital and is about to undergo a brain-imaging process that involves placing him inside a magnetic field so that a computer can create three-dimensional images of his brain. What procedure is he about to undergo?

Answers

Answer:

Magnetic resonance imaging (MRI)

Explanation:

Magnetic Resonance Imaging is one of the most widely performed exams in the world at the most modern medical centers and has revolutionized the diagnosis, used in virtually all medical specialties and for patients of all ages, even babies.

It is an exam that does not use radiation, but acquires the information provided by the magnetic field and radiofrequency waves generated by the machine and translated by a special computer. Every day new and better techniques are launched creating detailed images for disease research and treatment follow-up. In short, magnetic resonance imaging is a procedure where a patient is placed within a magnetic field so that a computer can create three-dimensional images of his brain, or other body part that needs to be examined.

How would the Americans with Disabilities Act​ (ADA) be satisfied for a pregnant emergency medical dispatcher​ (EMD) who suffers from paralysis of both legs and requires the use of a​ wheelchair?
a. Wheelchair accessibility to and from dispatchb. Hourly pay rate 10 percent above the other EMDsc. Scheduled shifts during daylight hours onlyd. Transport by your service to and from work

Answers

Answer: a. Wheelchair accessibility to and from dispatch.

 

Explanation:

The Americans with Disabilities Act has became a law in the year 1990. The ADA secures the rights law that restricts the discrimination against individuals with the disabilities in all regions and area of social dealing. For providing the medical assistance to the pregnant women affected by paralysis a wheelchair should be provided so as to secure easy and injury free dispatch.

The track coach notices that his star runner is running quicker than ever before, but quickly gets tired and shows evidence of depression after the race. The coach should suspect that the runner might be taking __________.

Answers

Final answer:

The track coach should suspect the use of performance-enhancing drugs due to the runner's quick performance improvement, followed by increased fatigue and signs of depression, which are common side effects.

Explanation:

The track coach notices that his star runner is running quicker than ever before, but quickly gets tired and shows evidence of depression after the race. The coach should suspect that the runner might be taking performance-enhancing drugs. Performance-enhancing drugs, while they can initially boost physical capabilities, often have serious side effects such as increased fatigue post-exertion and mood disorders, including depression. The quick improvement in performance coupled with the negative side effects hints at the possible use of such substances. Coaches and medical professionals should approach the situation with sensitivity and support, seeking medical advice and promoting healthy, natural ways to improve performance and manage mental health.

Alice is looking for an effective diet program. She is able to evaluate the claims of competing programs in an open-minded and careful fashion by __________, the hallmark of scientific skepticism.
a. using her critical thinking skillsb. being open to metaphysical reasoningc. using her common sense and intuitiond. remembering that extraordinary claims require ordinary evidence

Answers

Answer:

it a. using her critical thinking skills

Explanation:

The nurse attempts to notify a health care provider about a client’s elevated temperature but does not get a response. Which statement, if documented by the nurse, would indicate that the nurse is following proper protocol for nursing documentation?

Answers

Answer:

1300: Client temperature elevated. Telephoned health care provider's service 3 times without a response. Tepid sponge bath given and nursing supervisor notified.

Explanation:

A healthy adult is expected to have an average body temperature around 37 ° C. Values above 38ºC in healthy people represent hyperthermia, which is the loss of the ability to control body temperature, resulting in a marked increase in a patient's body temperature. This increase, considered severe when the body temperature exceeds 40ºC, deregulates the whole organism and affects body systems, which can have serious consequences. When an inpatient has a very high body temperature, nurses must notify the doctor promptly so that the necessary procedures are applied.

If the nurse contacts a physician for a case of a patient with a high body temperature, and the physician does not respond to contact, the nurse should follow the appropriate protocol and document the case as:

1300: Client temperature elevated. Telephoned health care provider's service 3 times without a response. Tepid sponge bath given and nursing supervisor notified.

Final answer:

Proper protocol for nursing documentation when a health care provider does not respond includes recording the communication attempt, method, time, and lack of response. The nurse should also document any patient interventions and plans for follow-up, ensuring accountability and continuity of care.

Explanation:

The proper protocol for nursing documentation in the case where a nurse does not get a response from the health care provider about a client's elevated temperature would be to record the attempt to communicate the issue, the method used, the time, and the lack of response. Documentation might include statements such as "Notified Dr. Smith of patient's elevated temperature at 10:00 AM via voicemail; no response as of 10:30 AM." This indicates the nurse's follow-up and ensures accountability, showing due diligence in trying to reach the health care provider and keeping clear and accurate records for future reference.

The nurse should also document the patient's condition, any interventions taken, and the plan to re-attempt communication or escalate the concern if necessary. Proper documentation is crucial for legal reasons and also for ensuring continuity of care. By recording events accurately and promptly, the nurse fulfills a professional responsibility and facilitates effective communication among healthcare team members.

If your client can successfully complete two or more repetitions above the desired repetition range in the last set in two consecutive workouts for any given exercise, the load should be ___, depending on your client’s current physical abilities. increased
a. by 1-5% increased
b. by 2-10% increased
c. by 5-15% increased
d. by 10-20% none of these

Answers

Answer:

b. by 2-10% increased

Explanation:

When we talk about gym training, whether it's simple weight training or some specific strength training, a lot of people think more about the load and the amount of repetitions than the perfect execution of the movement. It can be risky, especially if you have never done the exercise before. In any exercise of your workout, keep in mind that you first need to learn the correct movement. Then execute it with mastery, only then increase the load and repetitions. And, if you did or do without coaching guidance, there is a great chance you are doing it wrong.

Thinking about this, if your client can successfully complete two or more repetitions above the desired repetition range in the last set in two consecutive workouts for any given exercise, the load should be by 2-10% increased, depending on your client's current physical abilities.

Stress may increase your risk for which of the following: A. Heart disease B. High blood pressure C. A stroke D. All of the above

Answers

Answer:

i believe its option a.

sorry if im wrong

Answer:d( all of the above)

Explanation:because stressing can cause all of them

Holly was dancing with her new boyfriend at an Elvis tribute. When the band started playing "Cant Help Falling in Love with You" her boyfriend gave her a long, passionate kiss, which Holly found very enjoyable. Now Holly finds that every time she hears "Cant Help Falling in Love with You" on the radio, she becomes a little flushed. In this example, the conditioned stimulus is the song "Cant Help Falling in Love with You". So is the Conditioned response she becomes a little flushed or when she hears it playing? Is the unconditioned stimulus dancing with her boy friend? and the unconditioned response enjoyable?

Answers

Answer:

the song, "Cant Help Falling in Love with You"

Explanation:

which of these best describes the perceived body image of a person suffering from anorexia nervosa

Answers

Answer:

They would see themselves as overweight even if they were thin.

Explanation:

people with anorexia nervosa think that they are overweight they have body dysmorphia

The nurse is preparing a child for discharge following a sickle cell crisis. The mother makes the following statements to the nurse. Which statement by the mother indicates a need for further teaching?a) "She loves popsicles, so I'll let her have them as a snack or for dessert."b) "I put her legs up on pillows when her knees start to hurt."c) "She has been down, but playing in soccer camp will cheer her up."d) "I bought the medication to give to her when she complains of pain."

Answers

Answer:

c) "She has been down, but playing in soccer camp will cheer her up."

Explanation:

The nurse is preparing a child for discharge following a sickle cell crisis. The mother makes the following statements to the nurse. Therefore, the statement given by the mother indicates a need for further teaching is, "She has been down, but playing in soccer camp will cheer her up."

Chris drinks coffee frequently. If she tries to get through the day without a cup of coffee, she feels tired and groggy. Chris's feelings of fatigue and drowsiness are most likely _____ that are caused by a phenomenon called the _____ effect.

Answers

Answer:

withdrawal symptoms, drug rebound

Explanation:

Months after she was beaten up by a robber. Courtney's heart pounds with fear merely at the sight of the place in which she was attacked. The location of her attack is most likely a(n) __________ for Courtney's anxiety.

Answers

The answer is a trigger.

Agoraphobia is the anxiety disorder affecting Courtney's fear of the location where she was attacked.

Agoraphobia is the condition that describes Courtney's anxiety towards the location where she was attacked. This anxiety disorder is characterized by feeling that a place is uncomfortable or unsafe, making escape difficult or embarrassing.

People suffering from agoraphobia may avoid places associated with past trauma, like Courtney's fear of the location where she was attacked. This avoidance behavior is a common feature of this anxiety disorder.

Maricella was born several days ago, and her pediatrician has observed that she has almond-shaped eyes and a fold over her eyelids. In addition, her head, neck, and nose are smaller than other babies of her birth weight. It is most likely that Maricella has an extra of the _____ pair of chromosomes.
a.4th
b.9th
c.17th
d.21s

Answers

Hi !

It is most likely that Maricella has an extra of the " 21" pair of chromosomes.

A teacher wants to know if alcohol improves test performance. He separates 24 students into three groups by random assignment. Group 1 is sent to a study group for 3 hours before the test. Group 2 is sent to the gym for three hours before the test, and Group 3 is sent to a bar for three hours before the test. After the three hours, the students are tested. What would be the best statistical test to show if alcohol had any affect between the three groups?

Answers

Answer:

ANOVA

Explanation:

According to my research on different statistical tests, I can say that based on the information provided within the question the best test would be ANOVA. Analysis of variance (ANOVA) is a collection of statistical models and their associated estimation procedures used to analyze the differences among group means in a set of data. Which is the best method when analyzing three groups, while for 2 groups the best method would be an independent t-test.

I hope this answered your question. If you have any more questions feel free to ask away at Brainly.

Answer:

anova

Explanation:

A person wears a hearing aid that uniformly increases the intensity level of all audible frequencies of sound by 30.0 dB. The hearing aid picks up sound having a frequency of 100 Hz and an intensity of 1.3e-10 W/m2. What is the intensity delivered to the eardrum?

Answers

Answer:

The intensity delivered to the ear drum is I' = 653.131x10^-11 w/m^2

Explanation:

The standard intensity Io = 10^{-12} w/m^2

The intensity of [tex]1.63 \times 10^{-10}[/tex] corresponds to an intensity level of

[tex]10 log[\frac{I}{Io}] = 10 log[\frac{(1.3\times 10^{-10}}{10^{-12}}] = 11.13 dB[/tex]

This is increased by the hearing aid by a factor of 30 dB

It now becomes 30 + 11.13 = 41.13 dB

This corresponds to an intensity of I'

10 log(I'/Io) = 41.13 dB

log (I'/Io) = 4.11

I'/Io + 10^4.11

I' = 10^{-12} x 12882.49 w/m^2

The intensity delivered to the ear drum is

I' = 653.131x10^-11 w/m^2

The intensity level at the eardrum is 1.3 × 10⁻⁷ W/m²

Sound intensity level

The sound intensity level is given by L = 10㏒(I/I₀) where

I = intensity and I₀ = reference intensity

Now given that

I = intensity at eardrum, I₀ = intensity of hearing aid = 1.3 10⁻¹⁰ W/m² and L = 30 dB (since the hearing aid that uniformly increases the intensity level of all audible frequencies of sound by 30.0 dB and thus the difference in their sound levels)

Since  L = 10㏒(I/I₀)

Intensity at eardrum

Making I subject of the formula, we have

[tex]I = I_{0} (10^{\frac{L}{10} } )[/tex]

Substituting the values of the variables into the equation, we have

[tex]I = I_{0} (10^{\frac{L}{10} } )[/tex]

[tex]I = 1.3 X 10^{-10}W/m^{2} (10^{\frac{30}{10} } )\\I = 1.3 X 10^{-10}W/m^{2} (10^{3} )\\I = 1.3 X 10^{-7}W/m^{2}[/tex]

So, the intensity at the eardrum is 1.3 × 10⁻⁷ W/m²

Learn more about sound intensity here:

https://brainly.com/question/17062836

During a typical morning, Daniel will check the clock more frequently as the time for his regularly scheduled lunch break approaches. In this case, Daniel's clock-checking behavior is reinforced on a ________ schedule.A. variable-interval
B. fixed-ratio
C. fixed-interval
D. variable-ratio

Answers

Fixed Interval Schedule

True / False: Gathering behavioral information on readiness to change and decisional balance should follow after completing a health-risk assessment on an individual.

Answers

Answer:

False

Explanation:

Behavioral information collection should be done before and not after the completion of an individual's health risk assessment. This is because behavioral information is important data for assessing an individual's health levels and risk levels. There is no possibility that a conclusion to an individual's health risk assessment would be effective if the individual's behavioral information collection had not been done before.

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