Adults with more than a 12-month history of migraines were assigned randomly in a double-blinded study to receive treatment with experimental drug X (10 or 20 mg/day) or placebo. The primary efficacy measure was the reduction in severity of the migraine attacks. Enrollment was 1,200 subjects. Which of the following best describes the clinical phase of this study?

Answers

Answer 1

Answer:

Phase III

Explanation:

The given condition fall in the trial phase (Phase III) of cinical study which aims to:

- Determine drug's effectiveness (primary goal)

- Determine long-term drug safety

- Confirm findings

In Phase III, randomised, double-blind, placebo-controlled, parallel group study is majorly to evaluate the efficacy and safety of placebo in episodic migraine prevention in children (6 to < 12 years of age) and adolescents (12 to < 18 years of age).  

The trial consists of four phases: screening; double-blind therapy period for 24 weeks in which placebo or Erenumab is given to subject as dose 1, dose 2 or dose 3 (based on the participant's body weight) once a month via subcutaneous injection; optional dose level blinded extension phase (40 weeks) which involves subjects recieve dose1, 2 and 3 of placebo, and at last it follows a safety follow-up phase for 12 weeks (after 16 weeks  of the last dose of investigational drug).

Hence, the clinical phase is phase III.

Answer 2

The study described can best be classified as b. Phase III clinical trial.

Here’s why:

Enrollment of 1,200 subjects - Phase III trials typically involve a larger number of patients, usually ranging between 1,000 and 3,000 participants. This is consistent with the enrollment figure given in the study.

Primary efficacy measure - Phase III trials are designed to establish the efficacy of a new drug compared to existing treatments or a placebo. In this case, the primary efficacy measure is the reduction in severity of migraine attacks, which aligns with the goals of a Phase III trial.

Double-blind study - Double-blind studies are a hallmark of Phase III clinical trials. In such studies, neither the participants nor the researchers know who is receiving the experimental drug and who is receiving the placebo. This is done to eliminate bias and ensure the reliability of the results.

Experimental drug X vs placebo - Comparing the experimental drug to a placebo is a standard approach in Phase III trials. This helps determine the drug’s therapeutic effect and its benefits versus risks.

Complete question:

Adults with more than a twelve (12)-month history of migraines were assigned randomly in a double-blinded study to receive treatment with experimental drug X (10 or 20 mg/day) or placebo. The primary efficacy measure was the reduction in severity of the migraine attacks. Enrollment was twelve-hundred (1200) subjects. Which of the following best describes the clinical phase of this study?

a. Phase II b. Phase III c. Preclinical d. Phase I


Related Questions

The Punnett square shows the possible genotype combinations for the offspring of two parents.
What are the genotypes of the parents?
A Gg and Gg
B GG and GG
C gg and gg
D Gg and gg

Answers

Answer:

A or just Gg and Gg

Explanation:

I'm taking the test

The Punnett square shows the possible genotype combinations for the offspring of two parents, and the genotypes of the parents are Gg and Gg, which are in option A, and due to this, there are three types of offspring present.

What is the relationship between the parents and offspring?

Parents and offspring are very closely related as the parents produce gametes that are united to form the zygote, and that zygote develops into the offspring, the child, or the plant, and here are four offspring that are present. Out of four offspring, one is GG, two are Gg, and one is gg, and this is only possible when the heterozygous parents are present.

Hence, the Punnett square shows the possible genotype combinations for the offspring of two parents, and the genotypes of the parents are Gg and Gg, which are in option A, and due to this, there are three types of offspring present.

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How do endocrine glands help the body maintain homeostasis

Answers

Answer:

They control body activities by releasing hormones into the blood.

Explanation:

The endocrine system produces hormones which maintain our blood sugar level (homeostasis) .  The pancreas is the main gland involved.

If our blood sugar level increases the pancreas detects this and insulin is then released which acts on our liver.  The excess glucose is then converted to glycogen.

Excessive  Glucose →  Glycogen

If our blood sugar level decreases , again the pancreas detects it and releases glucagon which act on the liver.  The excess glycogen is then converted to glucose.

Excessive Glycogen  →  Glucose

The reason this system is vital is because our brain needs glucose and if the endocrine system is not working, our brain will cease to work efficiently and will ultimately shut down due to lack of glucose supply.

What is not a similarity between the male and female reproductive systems?

Answers

the male consists of external organs
the female consists of internal organs

Plasmids have a high probability of being present in the new generation of cells by all of the following EXCEPT: A. being present at a high number so that some copies will end up in each new cell after cell division B. by having a mechanism to allow for segregation of plasmids into daughter cells C. carrying a gene or genes essential for survival D. all are plausible mechanisms that could ensure maintenance of a plasmid in the population

Answers

Answer: C. carrying a gene or genes essential for survival

Explanation:

A plasmid can be defined as the small, extrachromosomal, double stranded DNA that can be found in the bacterial cell and in other prokaryotes. The plasmid DNA remain physically separated from the chromosomal DNA. The plasmid DNA can replicate independently.

The plasmid DNA carries genes which can facilitate the survival of the organism. This gene may provide the selective advantage like antibiotic resistance to the bacteria or any other organism. But the gene may not be essential for the survival of the organism.

What is the advantage of a fungal body being composed of numerous thin hyphae instead of one or two very thick hyphae?

Answers

Answer:

A greater surface area is available for absorption of nutrients.

A dorsal and ventral root of each spinal segment unite to form a

Answers

Answer:

A dorsal and ventral root of each spinal segment unite to form a spinal nerve.

Explanation:

Spinal nerves are the mixed nerves emerging from the spinal cord and exiting at the intervertebral foramen.A dorsal and ventral root of each spinal segment unite to form a spinal nerve.

Proximal branches of the spinal nerve includes:

Dorsal (posterior) root is sensory input to spinal cordVentral (anterior) root is motor input of spinal cord.

Distal branches :

Dorsal ramus supplies the dorsal body ,muscle and skin.Ventral ramus to ventral skin and muscles and limbs.Meningeal branch to meninges, vertebrae and ligaments.

Final answer:

The dorsal root (comprising sensory axons) and ventral root (comprising motor fibers) of each spinal segment combine to form a spinal nerve, crucial in communication between the spinal cord and the body.

Explanation:

In biology, particularly in the study of the nervous system, the dorsal and ventral roots of each spinal segment unite to form a spinal nerve. These spinal nerves are instrumental in transmitting sensory and motor information between the spinal cord and the rest of the body. The dorsal root contains sensory axons which enter the spinal cord, while the ventral root contains motor fibers that emerge from it. Together, these two roots form a spinal nerve, which is an integral component of the peripheral nervous system.

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What is the scientific name of an organism is made up of what two group names

Answers

Prokaryotes and Eukaryotes

You are performing developmental studies during which you extract mesophyll cells from an unusual-looking leaf. In laboratory culture, individual mesophyll cells from this leaf can be induced to regenerate entire plants. How would these cells be classified

Answers

Answer:

meristematic cells

Explanation:

The cells will be classified as meristematic cells.

Meristematic cells are undifferentiated cells that are capable of actively dividing and differentiating to give rise rise various tissues/organs of a plant.

Generally in plants, meristematic cells are of three types:

Those that are capable of dividing and differentiating to give rise to above ground or below ground tissues/organs such as roots, leaves and flowers, also known as apical meristems.Those that allow rapid stem elongation and repair, especially in monocots, also known as intercalary meristems.Those that give rise to various parts of a flower, also known as flora meristems.

The cells in this case are capable of dividing and differentiating to give rise to the various organs of a complete plant. Hence, they are considered as meristematic cells.

Incontinetia pigmenti is an x-linked dominant condition. homozygotes and hemizygotes die in utero. in infancy ip causes blistering of parts of the skin, and patchy altered pigmentation later. a woman with ip has a newborn child. what is the chance that newborn will be an unaffected girl?

Answers

Answer:

Option A

Explanation:

Complete Question

Incontinetia pigmenti is an X-linked dominant condition. Homozygotes and hemizygotes die in utero. In infancy IP causes blistering of parts of the skin, and patchy altered pigmentation later. A woman with IP has a newborn child. What is the chance that newborn will be an unaffected girl?

a. 1/4

b. 1/3

c. 1/2

d. 2/3

e. 3/4

f. Impossible to know without more information.

Solution

As we know that an X-linked dominant inheritance is a kind of genetic condition in which X linked mutant is a dominant trait. Thus, even if one copy of X chromosome is present, the offspring would be diseased individual.  

Here , Given

Woman has ip, hence in order to have unaffected girl child she must mate a normal man

Genotype of woman would be XX'

Genotype of man would be YX

XX' * YX

XY, XX, X'Y. X'X

Two daughter and two son will be produce.

Out of the two daughters one is diseased and another one is normal.

Thus, the chance that newborn will be an unaffected girl is

[tex]\frac{1}{4}[/tex]

Thus, option A is correct

 

Which best describes how the common cold spreads in the human body

Answers

Explanation:

"The best description how the common cold spreads in the human body is by the replication of virus inside the respiratory track (cells of respiratory tract) of the body."

Answer: Viruses replicate inside respiratory cells.

It's right plz click thanks for more ans!!! :-)

Choose the the option that best describe how cytokinesis works in animal and plant cells.
1. Animal cells: A cell plate forms along the equator of the parent cell and a new cell wall and plasma membrane form on either side of the plate.
2. Animal cells: The plasma membrane pinches in along the parent cell's equator to form two daughter cells.
3. Plant cell: The plasma membrane pinches in along the parent cell's equator to form two daughter cells.

Answers

Answer is Option "1"

Explanation:

In animals, cell division occurs when a band of cytoskeletal strands called the contractile ring contracts internal and squeezes the phone in two, a procedure called contractile cytokinesis. The space created as the ring contracts internal is known as the cleavage wrinkle. Creature cells can be squeezed in two because they're relatively soft and squishyPlant cells are much stiffer than animal cells; they're encompassed by an inflexible cell divider and have high inside weight. Along these lines, plant cells separate in two by building another structure down the center of the cell. This structure, known as the cell plate, is comprised of plasma layer and cell wall segments conveyed in vesicles, and it parcels the cell in two

Final answer:

Cytokinesis differs in animal and plant cells; animal cells form a cleavage furrow through actin filament contraction to divide, while in plant cells, a cell plate forms from Golgi vesicles, leading to the formation of separate plasma membranes and new cell walls.

Explanation:

The process of cytokinesis differs between animal and plant cells. In animal cells, cytokinesis involves the formation of a contractile ring of actin filaments just inside the plasma membrane at what was the metaphase plate during mitosis. The ring contracts, creating a cleavage furrow that deepens until the cell is pinched in two, creating two separate daughter cells.

In contrast, during plant cell cytokinesis, Golgi vesicles gather at the former metaphase plate, forming a structure known as the phragmoplast. From here, a cell plate begins to form that extends outward toward the existing cell walls. Eventually, the membranes from these vesicles fuse to create a new plasma membrane, effectively splitting the cell into two. A new cell wall is then constructed along each side of this cell plate, finalizing the division.

Heather and Haley are modeling the movement of a wave using a rope. When Heather gives one end of the rope a quick up and down shake, a wave travels down the rope toward Haley. Look at the picture of the rope model shown below.


Which arrow in the picture shows the amplitude of the wave?
A.
W
B.
X
C.
Y
D.
Z

Answers

Answer:

The answer is y

Explanation:

The energy that flows through most ecosystems comes from the sun. primary producers convert a fraction of the sun's energy into chemical energy, which can be used by consumers. food webs describe how energy flows between trophic levels in an ecosystem, and a trophic pyramid represents the amount of energy available at each trophic level. part a - identifying trophic levels in a food web

Answers

Answer:

Primary producers (autotroph organism), primary consumers (herbivores), secondary consumers (carnivores), decomposers

Explanation:

The trophic web is the process of energy transference through a series of organisms, in which every organism feeds on the preceding one and becomes food for the next one. The first link is an autotroph organism or producer, such as a vegetable, that can synthesize organic matter from inorganic matter. The next links are the consumers: herbivores are primary consumers and feed on producers. Carnivores are secondary consumers and feed on herbivores, and so on. The last links are the decomposers, microorganisms that act on dead animals degrading organic matter.

When one of the links disappears, it affects the superior links as they will not have their food source. The immediately anterior link will be beneficiated, as it will not be eaten by its predator. And finally, as this last link will overgrow, it will consume greater quantities of its food, causing a decrease in its anterior link.

Final answer:

The energy flow in ecosystems starts with the sun and is converted into chemical energy by primary producers. Consumers obtain this energy by consuming the primary producers. Food webs and trophic pyramids describe the flow of energy between trophic levels in an ecosystem.

Explanation:

In most ecosystems, the energy flow starts with the sun. This energy is converted into chemical energy by primary producers through the process of photosynthesis. Consumers, such as herbivores, then obtain this chemical energy by consuming the primary producers.

The energy transfer between trophic levels is described by food webs, which illustrate the feeding relationships in an ecosystem. Trophic pyramids represent the amount of energy available at each trophic level, with energy decreasing as you move up the pyramid.

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In the facilitation model of succession A. Later species facilitate the persistence of pioneers. B. Early species facilitate the next disturbance. C. Early species facilitate colonization by later species. D. Late species facilitate dispersal by early species. E. None of the above.

Answers

Answer:

Option-C

Explanation:

Ecological Succession is the phenomenon by which the ecosystem develop and change over time. The ecological succession represents the pathway which shows how the ecosystem of a particular area has changed.

The classical model for this succession is known as the facilitation model which suggests that the initial species or the pioneer species which have established in the area modified the area for survival which facilitated the other species to grow there. Once the pioneer species modified the area, the later species colonized the area and flourished.

Since early species facilitate colonization of the later species, therefore, is the correct answer.

Which does not indicate a chemical change has occurred:

Change of color
Heat is produced
Smell is produced
Light is produced
Gas is produced
Solid is produced

Answers

Answer:

Light is produced

11
TL 4
5
6
7
sun —
grass
grasshopper-
shrew
Owl
3.Explain why this food chain is not complete.​

Answers

What areis the answer

What leads to the degradation of the contents of late endosomes by lysosomal enzymes?

Answers

Answer:

It forms with fragments of the "early endosomes" or migration endosomes, near the Golgi apparatus, it has a more central location within the cell and a slightly more acidic pH than the "early endosome". The latter will allow it to facilitate the function of the hydrolytic enzymes it receives from the Golgi apparatus, thus finally forming the lysosomes, organelles specialized in degradation.

In transport through "transcytosis", the endocited material is transported in endosomes from one end of the cell to the other, being released by the process called exocytosis.

Explanation:

Endosomes are not considered cellular organelles by many authors, but compartments within the cytoplasm that function as transporters of material in animal and fungal cells delimited by a simple clathrin membrane, mediated by a receptor in the extracellular domain at the starting site invagination; but recent literature does classify them as structures with sufficient characteristics to be considered organelles. They are defined as membranous organelles and most of the material they transport is transferred to lysosomes for degradation.

What weather conditions would exist in El Paso based on the weather map seen here?

Answers

Answer:

Dry and hot

Explanation:

an organism inherits it’s genetic material from it’s-
1. offspring
2. food source
3. parents
4. environments

Answers

Parents, genetic material is only ever passed through reproduction.

Final answer:

An organism inherits its genetic material from its parents via genes on the chromosomes, with variations contributing to diversity among offspring. The environment and mutations also play a role in determining characteristics and evolutionary changes.

Explanation:

An organism inherits its genetic material from its parents. This genetic material comes in the form of DNA, where genes are the units of inheritance that determine an organism's characteristics. Each parent contributes one set of genes, which are located on chromosomes, thus providing two copies of each gene to their offspring. Variations in these genes, known as alleles, contribute to the diversity among siblings.

The process of inheritance is universal among cellular organisms, ensuring that the offspring will belong to the same species and will exhibit similar characteristics such as size and shape. While genetic inheritance is a major factor, it is important to understand that the environment can also influence characteristics through mechanisms like fetal programming and intergenerational inheritance.

Additionally, genetic variation arises due to mutations during DNA replication and environmental factors such as UV radiation. Over time, these variations can lead to significant evolutionary changes, as those with beneficial alterations are more likely to survive and reproduce, passing their traits to the next generation.

Lateral gene transfer involves the movement of genes between members of a species without sexual reproduction. In bacteria, there are three mechanisms for this: Conjugation, transformation, and transduction. Predict how these processes are most likely to affect bacteria

Answers

Answer:

Transformation is a genetic mechanism for which the bacteria incorporate DNA from its cellular medium

Transduction is another genetic mechanism for which DNA is transferred among bacteria by viruses

In conjugation, DNA is transferred between cells, which are named donor and recipient cells

Final answer:

Horizontal gene transfer plays a critical role in bacterial adaptation and evolution, involving mechanisms such as transformation, transduction, and conjugation. These processes contribute to genetic diversity, spread antibiotic resistance, and enable bacteria to adapt to new environments.

Explanation:

Horizontal gene transfer (HGT), also known as lateral gene transfer, has significant implications for bacterial evolution and adaptation. Bacteria can acquire new genes through three primary mechanisms: transformation, transduction, and conjugation. These processes allow bacteria to gain genetic material without sеxual reproduction and can lead to increased genetic diversity, the spread of antibiotic resistance, and the ability to inhabit new ecological niches.

During transformation, bacteria take up nаked DNA from their environment, which often comes from dead bacteria releasing their genetic material. This DNA can be incorporated into the recipient's genome, leading to genetic variation within the population. Transduction occurs when a virus transfers genetic material between bacteria, facilitating the spread of genes between distinct bacterial populations. Lastly, conjugation, the most common form of HGT, involves the direct transfer of DNA from one bacterium to another through a pilus. It can result in the dissemination of genetic traits, such as antibiotic resistance, across diverse bacterial species.

These HGT mechanisms have substantial ecological and medical consequences as they contribute majorly to bacterial adaptability and the emergence of multidrug-resistant strains. Furthermore, such gene transfer events are often more rapid than mutation-driven evolution, prompting rapid bacterial response to environmental changes such as the introduction of new antibiotics.

Which cells form the stomata in a plant ? Help please

Answers

Answer:

parenchyma cells

Explanation:

The xylem and the phloem

Two populations of birds with somewhat different coloration live on opposite sides of a peninsula. The habitatbetween the populations is not suitable for these birds.When birds from the two populations are brought together,they produce young whose appearance is intermediate between the two parents. These offspring will breed with eachother or with birds from either parent population, and all offspring of these pairings appear intermediate to variousdegrees.What keeps the two populations separate?

A.temporal reproductive isolation
B.lack of hybrid viability
C.behavioral reproductive isolation
D.spatial reproductive isolation—the only reason these two species don’tmate is because of the inability of the middle land to be occupied

Answers

Answer:

Option D, spatial reproductive isolation—the only reason these two species don’t mate is because of the inability of the middle land to be occupied

Explanation:

It is clear from the question that the two bird populations with different color are able to mate and reproduce viable and fertile offspring when brought together. Hence, the only problem due to which these two bird population were not breeding with each other was their distant location and habitat.

Location and habitat are characteristic of spatial distribution and hence they were separate because of spatial reproductive isolation

Hence, option D is correct

Final answer:

D. Spatial reproductive isolation keeps two bird populations with different colorations separate due to an unsuitable habitat preventing interaction and breeding, leading to independent evolution and potential reinforcement of isolation.

Explanation:

The reason the two populations of birds with different colorations remain separate is due to spatial reproductive isolation. This form of reproductive isolation occurs when two populations are geographically separated by an unsuitable habitat, preventing them from interacting and breeding. In this scenario, the unsuitable habitat between the bird populations functions as a barrier, keeping them genetically and reproductively independent even though they can produce viable offspring when brought together artificially.

Habitat isolation ensures that each population can evolve independently through natural selection, mutation, and genetic drift. As a result, even if the two populations were to come into contact again, they might be so genetically distinct that interbreeding would no longer be feasible, leading to the reinforcement of isolation.

Chantel dropped a tiny spot of ketchup on her pants during lunch. Even though her teacher was able to completely remove the spot, Evelyn is crying hysterically and says that she wants to go home because her outfit is ruined. Her behavior demonstrates the characteristic of preoperational thought known as ____________.
A. Irreversibility
B. Animism
C. Egocentrism
D. Conservation

Answers

Answer:

A. Irreversibility

Explanation:

Based on the scenario being described it can be said that her behavior demonstrates the characteristic known as irreversibility. This refers to a stage in early child development in which the child believes that certain actions/events cannot be reversed or undone, such as spilling ketchup on her dress. Chantel believes that the dress cannot be fixed and is why she begins to cry uncontrollably.

One day, you ride your bike to a local bookstore. You purchase a few of your favorite comic books, put them in your backpack, and ride home. Once you get home, you sit in a rocking chair and read your comic books.

Which resource in this scenario is nonrenewable?

Answers

Answer: The steel frame to make the bike

Explanation:

it is a natural resource that cannot be replaced,

Answer:

A.

Explanation:

i did the assignment on edgenuety

Sickle-cell anemia is a genetically inherited disease. Homozygous individuals (SS) have normal blood cells that are easily infected with the malarial parasite. Thus, many of these individuals become ill and may die. Individuals homozygous for the sickle-cell trait (ss) have sickled red blood cells that readily collapse when deoxygenated. Although malaria cannot grow in these red blood cells, individuals often die because of the hemoglobin disorder. However, individuals with the heterozygous condition (Ss) have some sickling of red blood cells, but generally not enough to cause death. In addition, the heterozygotes tend to survive better than either of the homozygous conditions as they are resistant to malaria. If 16% of an African population is born with a severe form of sickle-cell anemia (ss), what percentage of the population will be heterozygous (Ss) for sickle-cell and therefore resistant to malaria?

Answers

Final answer:

The percentage of the population that will be heterozygous (Ss) for sickle-cell and therefore resistant to malaria is 84%.

Explanation:

To calculate the percentage of the population that will be heterozygous (Ss) for sickle-cell and therefore resistant to malaria, we need to find the frequency of the ss genotype first. Given that 16% of the population is born with a severe form of sickle-cell anemia (ss), the frequency of the ss genotype is 0.16.

Since we are dealing with a single gene with two alleles, the sum of the frequencies of all possible genotypes should equal 1. So, to find the frequency of the Ss genotype, we can subtract the frequency of the ss genotype from 1.

Frequency of Ss = 1 - Frequency of ss = 1 - 0.16  = 0.84.

Finally, to get the percentage, we can multiply the frequency by 100.

Percentage of the population that will be heterozygous (Ss) = Frequency of Ss x 100 = 0.84 x 100 = 84%.

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Which of the following is most likely to create genetic variation in a population?

a
RNA polymerase errors during transcription
b
Helicase failure to unwind DNA during replication
c
DNA polymerase errors during replication
d
Misincorporation of amnio acids by tRNA during translation

Answers

um maybe C dna polymerase errors during replication

Answer:

D

Explanation:

Genetic variation can be created by random mating, random fertilization, and recombination between homologous chromosomes during meiosis. I think b and c can be ruled out because they are relatively unlikely in themselves. D seems to be most likely due to RNA splicing and other methods that occur to avoid those errors.

Despite his young age, Ruben was recently diagnosed with hypertension. He knows that reducing dietary sodium and increasing dietary potassium can both help to lower his blood pressure. Of the following foods, which one contains the most potassium per servinga.Breadb.Bananac.peanutsd.potatoes

Answers

Answer:

Potato

Explanation:

Hypertension is a condition developed due to the continuous high or elevated blood pressure in the arteries in the body. The main cause of hypertension is the contraction of the arteries and the consumption of food with a high level of sodium and low level of potassium.

It is suggested that people with hypertension should consume a diet rich in potassium but with a low amount of sodium.  The good source of food with a high level of potassium is baked potato which provides carbohydrates also, salmon, and the banana.

Since the amount of potassium is high in the baked potato, therefore, is the correct answer.

Final answer:

Potatoes have the highest potassium content per serving among the listed foods and should be included in Ruben's diet to help manage his hypertension. It's also crucial to reduce dietary sodium to improve heart health.

Explanation:

Among the foods listed, potatoes contain the most potassium per serving. Potassium is an essential nutrient that plays a key role in maintaining proper heart function and regulating blood pressure. Ruben can benefit from eating potassium-rich foods, such as bananas, leafy greens, lima beans, and avocados, to help control his hypertension. It's also important to note that reducing dietary sodium intake and choosing foods lower in sodium can contribute to better blood pressure management.

Total recommended dietary potassium intake is 4700 mg/day. To improve the sodium and potassium balance in the diet, it's advised to avoid processed foods high in sodium and increase intake of fresh fruits and vegetables, which are generally high in potassium and other beneficial nutrients.

Our ability to oxygenate the tissues and organs of our bodies depends on our ability to ventilate, or exchange gases in our respiratory system. The resultant distribution of ventilation in our respiratory system depends on what factors?

Answers

Answer:

GravityBody position

Explanation:

Ventilation is defined as the exchange of air between atmosphere and the lungs so that the carbon dioxide in the alveoli (the small gas sacs in the lungs) can be exchanged.

Factors affecting distribution of air in respiratory system while ventilation are as following:

Gravity: Total blood flow and alveolar ventilation in the dependent lung is lower than in the non-dependent lung in the left lateral location, since the drop in lung volume outweighs any gravity-dependent ventilation and perfusion increases.Body position: Changing position is necessary to break through the daily monotonic delivery of mechanical ventilation and favour the clearance of respiratory secretions and results in the improvement of lung volume and oxygenation.

What is common between the environmental changes of ice ages and global warming?

Answers

Answer:

this may help!

Explanation:

The global climate is the connected system of sun, earth and oceans, wind, rain and snow, forests, deserts and savannas, and everything people do, too. The climate of a place, say New York, can be described as its rainfall, changing temperatures during the year and so on.

Answer:

It turns out that our warmth is the result of ocean currents that bring warm surface water up from the equator into northern regions that would otherwise be so cold that even in summer they'd be covered with ice.

Explanation:

Bacteria collected from a severely inflamed wound are sent to the lab for analysis. The results come back as follows: Gram-positive cocci in irregular clusters, kinase and coagulase positive, and able to grow in the presence of most antibiotics except vancomycin. The bacteria in the wound are most likely:

Answers

Answer:

Explanation:

Since the result shows the bacterial culture was irregular clusters of Gram-positive cocci, kinase and coagulase positive, it is should be Staphylococcus aureus and furthermore, it is able to grow in the presence of most antibiotics except vancomycin, the bacterial most likely methicillin-resiistant Staphylococcus aureus (MRSA). This organism is believed to harbor a chromosomal gene called mecA which confers on it the ability to be ressitant to methicillin and other β-lactam drugs antibiotics such as penicillin, cephalosporins  and carbapenems

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