If a person’s blood cortisol concentration is 10 µg/mL, and 10 mg of cortisol can be excreted from the body in a 24-hour period, what volume of blood plasma in mL was “cleared” during this amount of time?

Answers

Answer 1

Answer:

[tex]1000 ml[/tex] of blood plasma was “cleared”

Explanation:

Given,

Concentration of a person’s blood cortisol [tex]= 10[/tex]µg/mL

The amount of cortisol excreted from the body in a period of 24 hour [tex]= 10[/tex]mg

The volume of blood plasma cleared during this time period is equal to

amount of cortisol excreted from the body divided by Concentration of a person’s blood cortisol

The above definition could be represented as following-

volume of blood plasma cleared  [tex]= \frac{A}{B} \\[/tex]

Where A represents amount of cortisol excreted from the body

while B represents the concentration of a person’s blood cortisol

Substituting the given values in above equation, we get -

[tex]= \frac{10 * 10^{-3}g}{10*10^{-6}\frac{g}{ml} } \\= 1000 ml[/tex]

[tex]1000 ml[/tex] of blood plasma was “cleared”

Answer 2

The volume of blood plasma cleared of cortisol in 24 hours is calculated to be approximately 1000 mL. Clearance rate is found to be roughly 0.694 mL/min.

To find the volume of blood plasma that was "cleared" of cortisol in a 24-hour period, we must use the given values.

The blood cortisol concentration is 10 µg/mL, and 10 mg (which is equal to 10,000 µg) of cortisol is excreted in 24 hours.

Calculate the total amount of cortisol excreted in 24 hours: 10 mg = 10,000 µg.Use the formula for clearance, where clearance (C) is the volume of plasma cleared per minute (mL/min):

C = (Amount of Substance Excreted in 24 Hours) / (Concentration in Blood Plasma * Time in Minutes)

Substitute the known values into the formula:

C = 10,000 µg / (10 µg/mL x 1440 minutes)
C = 10,000 µg / 14,400 µg/mL
C ≈ 0.694 mL/min

Total Volume Cleared in 24 hours = Clearance Rate x Time
Total Volume Cleared in 24 hours = 0.694 mL/min x 1440 minutes
Total Volume Cleared in 24 hours ≈ 1000 mL

Hence, approximately 1000 mL of blood plasma was cleared of cortisol in this 24-hour period.


Related Questions

Explain the significance of retinal changes in a patient with high blood pressure.

Answers

Answer:

Explanation:

The retina is layer of tissues that surrounds the surface of the back of the eyeball. It consists of several layers that consists of photoreceptors which detects the color and intensity of light. The retina is affected by the blood pressure levels.

When the blood pressure becomes high the retina blood vessel may become thick. This may cause the blood vessels to become narrow, this restricts the flow of blood reaching the retina.

The high blood pressure may cause damage to the retinal blood vessels, as it restricts the function of retina. The high blood pressure inside the optic nerve may cause the problem of vision. This situation is called as hypersentive retinopathy.

Which of the meninges is a delicate connective tissue membrane that clings tightly to the brain like cellophane wrap following its every convolution?

Answers

Answer:

Pia mater

Explanation:

Three meninges cover the brain and spinal cord. Pia mater refers to the deepest meninx of the brain. It is a thin delicate layer of connective tissue. It is a transparent connective tissue layer like that of cellophane. Being a transparent and thin tissue layer, it looks like a cellophane wrap adhered to the surface of the brain.

The delicate connective tissue membrane that clings tightly to the brain and follows its convolutions is the pia mater, which is the innermost layer of the meninges.

The meninges are a series of protective membranes that cover the brain and spinal cord. Among the layers of the meninges, the innermost layer that clings tightly to the brain and follows its every convolution is called the pia mater.

This delicate connective tissue membrane is directly adjacent to the surface of the brain, fitting into the grooves and indentations of the cerebral cortex. The pia mater ensures that the brain's surface is well-protected, adapting to its intricate structures.

The other two layers of the meninges include the dura mater, which is the tough, fibrous, outermost layer, and the arachnoid mater, which is situated between the dura and pia mater and resembles a spider web.

Which of the following is an excitatory neurotransmitter secreted by motor neurons innervating skeletal muscle?
A) gamma aminobutyric acid
B) acetylcholine
C) cholinesterase
D) norepinephrine

Answers

Answer:

B) acetylcholine

Explanation:

Acetylcholine is an excitatory neurotransmitter secreted by motor neurons innervating skeletal muscle.

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