MAD protein are mutants cells and they can be refers to as mitotic arrest deficient. MAD protein act by recruiting the anaphase inhibitor MAD2 to dissociate kinetochores and its essentials from MAD2-CDC20 complex formation in vivo.
However, there mutation will produce defective protein and checkpoint failure by resulting into aneuploidy. Aneuploidy is when a cell finishes the process of mitosis and produces daughter cells with few or too many chromosomes and aneuploidy causes more than 90% of human cancer.
The potential outcome of a mutated MAD protein is development of aneuploidy in daughter cell.
Further Explanation:
The cell cycle is referred as the prearranged flow of steps that include the cellular division as well as cell growth. This cycle form two new daughter cells. The cycle is begins with the interphase. In this phase, mainly the cell replicates and matures its DNA.
The second stage of a cell cycle is the mitosis or M phase. Mitosis is a kind of cell division. In this, parental cells divide into two daughter cells which have the same number of chromosomes as that of the parent cell
MAD protein is a kind of a protein that mainly present in humans and this protein is encoded by MXD1 gene. This protein is mutant cell that is referred as mitotic arrest deficient. This protein has a role in recruiting an inhibitor MAD-2 which is anaphase inhibiter help in dissociating the kinetochores.
Development of any Mutations in the MAD protein can develop a defective protein and malfunction of the checkpoints. The cell ends the cell cycle by the last stage which mitosis. In the presence of mutated MAD protein daughter cell cannot develop properly. Daughter cell can have very low or high number of chromosome and can result in aneuploidy condition. Mainly aneuploidy cell develop or result in cancer cell.
Learn more:
1. Learn more about mitosis https://brainly.com/question/6462270
2. Learn more about the menstrual cycle https://brainly.com/question/723944
3. Learn more about meiosis https://brainly.com/question/94813
Answer Details:
Grade: High School
Subject: Biology
Chapter: Cell Cycle
Keywords:
Cell cycle, parent cell, mitosis, aneuploidy, daughter cell, protein, MAD, mutated protein, encoded, human, checkpoints, cancer cell, daughter cell, chromosome.
How many milligrams of arsenic would be a typical amount in a 60.-kg adult?
Final answer:
A typical 60-kg adult might have no more than 3 mg of arsenic, as it's an essential trace mineral thought to be required at levels less than 50 ppb to avoid toxicity.
Explanation:
The typical amount of arsenic in a 60-kg adult can be understood by looking at arsenic levels required for nutrition and when it becomes toxic. Arsenic is thought to be an essential trace mineral, with humans likely needing no more than 50 parts per billion (ppb). Considering the body weight, a typical 60-kg adult could thus be estimated to have no more than 3 milligrams (mg) of arsenic in their body to maintain essential physiological functions without reaching toxic levels. A toxic dose begins at approximately 7,000 ppb, which emphasizes the importance of the minute required quantity.
Exposure to arsenic can occur through various sources including contaminated drinking water, mining, agriculture, toxic waste, and even traditional medicines. Due to its potential to affect enzyme function, arsenic toxicity is a major concern; as such, testing for arsenic levels in urine, blood, or hair is implemented for diagnosis. These levels are used to ensure they stay within the non-toxic range for human health.
What is the function of the Compact Bone?
Final answer:
Compact bone is the dense external layer of bones that provides protection and strength. It consists of units called osteons, which are aligned parallel to the long axis of the bone. The osteons contain a mineral matrix, living osteocytes, and canaliculi that transport blood.
Explanation:
Compact bone, also known as cortical bone, is the hard external layer of bones and surrounds the bone marrow. Its main function is to provide protection and strength to bones. Compact bone tissue is made up of units called osteons, which are cylindrical structures that contain a mineral matrix and living osteocytes connected by canaliculi. These canaliculi transport blood and the osteons are aligned parallel to the long axis of the bone. Each osteon consists of layers of compact matrix called lamellae that surround a central canal called the Haversian canal, which contains the bone's blood vessels and nerve fibers. Compact bone tissue is located in areas of bone where stresses are applied in only a few directions, helping the bone resist bending or fracturing.
Assume that a drop in parasite abundance reflects an effective immune response by the host. explain the pattern you described in question 2.
Why does a desert have a dramatic change in temperature during the day and at night? Because
c. significally lower
i had the same question its the RIGHT ONE
A J-shaped curve is called a(n) _______.
Answer:
Exponential curve
Explanation:
The growth of population is represented with the help of population growth curves.An exponential growth curve is a J- shaped curve that shows the growth of the population in areas where there are unlimited resources present. In the presence of unlimited resources, there is a very fast growth of population however this growth decreases as the resources become limited.The pattern formed from such an increasing population size in the presence of unlimited resources results in a J-shaped exponential growth curve.Example- bacterial growthA nurse is preparing a 24-hour-old baby boy for circumcision. the hospital policy guidelines for circumcision support pain medication at least 1 hour prior to the start of the procedure. the provider did not order the pain medication. the provider arrives, and the nurse refuses to bring the baby for the circumcision stating that the pain medication was not ordered. which is the rationale for refusing to bring the baby for the procedure?
The nurse refused to bring the baby for the circumcision due to the lack of ordered pain medication, which the hospital policy states should be administered an hour beforehand to manage the newborn's high pain sensitivity.
The nurse's rationale for refusing to bring the baby for the circumcision procedure is based on the hospital's policy guidelines, which support administering pain medication at least 1 hour prior to the procedure to manage the infant's sensitivity to pain.
Immediately after birth, newborns are highly sensitive to touch and temperature, and they react strongly to pain with increased blood pressure, heart rate, and stress hormones. Without proper pain management, such as local anesthetics, the infant could experience significant distress and potential long-term effects.According to the dichotomous key, the organism pictured would be a member of the kingdom
Answer:
It's a Gibbon or orangutanExplanation:
I just assume because I answered a question like this if it's wrong I'm sorry...
A liver biopsy of a four-year-old boy indicated that the fructose-1,6-bisphosphatase enzyme activity was 20% of normal. the patient's blood glucose levels were normal at the beginning of a fast but then decreased suddenly. pyruvate and alanine concentrations were also elevated. explain the reason for this symptom.
The low fructose-1,6-bisphosphatase enzyme activity in the liver biopsy of the four-year-old boy leads to a decrease in glucose production during fasting. This deficiency impairs the conversion of fructose-1,6-bisphosphate to fructose-6-phosphate, causing a sudden decrease in blood glucose levels. The elevated pyruvate and alanine concentrations indicate the impairment of glycolysis.
Explanation:The fructose-1,6-bisphosphatase enzyme plays a crucial role in the breakdown of glucose during fasting. It converts fructose-1,6-bisphosphate into fructose-6-phosphate, an important step in glycolysis. In this case, the liver biopsy showed that the enzyme activity was only 20% of normal, leading to a decrease in glucose production.
Normally, during fasting, glucose is released from glycogen stores in the liver to maintain blood glucose levels. However, with reduced fructose-1,6-bisphosphatase activity, the body's ability to produce glucose is impaired, causing a sudden decrease in blood glucose levels.
This deficiency also leads to the accumulation of pyruvate and alanine because the conversion of fructose-1,6-bisphosphate to fructose-6-phosphate is compromised. These elevated concentrations further indicate the impairment of glycolysis.
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A mutation within a gene that will insert a premature stop codon in mrna would ________. result in a longer polypeptide chain result in a shortened polypeptide chain change the location at which transcription of the next gene begins have the same effect as deleting a single nucleotide in the gene
Answer:
Option B, result in a shortened polypeptide chain
Explanation:
Premature stop codon causes mutation which is called as non-sense mutation. In a non-sense mutation, the nonsense codon do not code for any amino acid instead they stop the coding and causes end of protein synthesis. Due to this, proteins are not synthesized to their full length and are also incomplete. These proteins are mostly nonfunctional, inactive and mutated.
Hence, option B is correct
Which characteristic sets hominins apart from other primates?
Several fish species became extinct millions of years ago. The graphs provided below show the distribution of fossils of these fishes as they occur in several undisturbed layers of sedimentary rock observable in a cliff face. Respond to ALL 4 PARTS below: Explain why the distribution of the fossils in figure 1 support the hypothesis that the extinction of these species was a result of a sudden environmental change. Describe an environmental change that could have produced this kind of fossil distribution. Explain why the distribution of the fossils in figure 2 supports the hypothesis that the extinction of these species was a result of a gradual environmental change. Describe an environmental change that could produce this kind of fossil distribution.
Vertebrates that are warm blooded, give live birth to live young, and nourish their young with milk would be classified as
Your answer is: Mammals
Ocean currents are caused by all of the following except:
underwater landslides
surface winds
tidal fluctuations
density contrasts in seawater
In mantle convection currents, hotter rock moves _______, while cooler rock moves _______.
Answer:In mantle convection currents, hotter rocks move ___upward___, while cooler rocks move ____downward____
Explanation:
What observation about light supported Einstein’s theory?
One point of view envisions light as wave-like in nature, producing energy that traverses through space in a manner similar to the ripples spreading across the surface of a still pond after being disturbed by a dropped rock. The opposing view holds that light is composed of a steady stream of particles, much like tiny droplets of water sprayed from a garden hose nozzle. During the past few centuries, the consensus of opinion has wavered with one view prevailing for a period of time, only to be overturned by evidence for the other. Only during the first decades of the twentieth century was enough compelling evidence collected to provide a comprehensive answer, and to everyone's surprise, both theories turned out to be correct, at least in part.
In the early eighteenth century, the argument about the nature of light had turned the scientific community into divided camps that fought vigorously over the validity of their favorite theories. One group of scientists, who subscribed to the wave theory, centered their arguments on the discoveries of Dutchman Christiaan Huygens. The opposing camp cited Sir Isaac Newton's prism experiments as proof that light traveled as a shower of particles, each proceeding in a straight line until it was refracted, absorbed, reflected, diffracted or disturbed in some other manner. Although Newton, himself, appeared to have some doubt about his corpuscular theory on the nature of light, his prestige in the scientific community held so much weight that his advocates ignored all other evidence during their ferocious battles
Answer:
The Sun bent the light from a star. This bending made the star appear in a slightly different position from its actual position. This observation supported Einstein’s theory.
Explanation:
This is the answer for Edmentum! :)
Which component of Earth's atmosphere is responsible for absorbing ultraviolet radiation? A. OZone B. Nitrogen C. Water vapor D. Oxygen
What is a primary reason an increase in glaciers on land would cause sea level to fall? g?
When a plant is using transpiration to cool off during the day, its stomates are _______ and its water potential is _______ that of the soil. at night, the plant's water potential will be _______ that of the soil (assuming that the soil is receiving sufficient moisture)?
When the body needs to conserve water, the kidneys excrete a hypertonic urine. what do the terms isotonic and hypertonic mean? since the fluid that is to become urine begins as plasma (an isotonic solution), what must happen to change it to a hypertonic urine?
Isotonic- In an isotonic solution the solvent and the solute are equal in concentration.
Hypertonic- contains more solvent than the solute. In cases of urine, it means there is more water concentration compared to solutes such as glucose, Na ions, Cl ions or Urea.
Process of changing isotonic solution (plasma) to hypertonic solution
Blood enters the kidney through the renal artery which separates many times segmental arteries to interlobular arteries to arcuate arteries to interlobular arteries to afferent arteries which deliver blood to nephron. Afferent arterioles has a greater diameter than the efferent(carries blood from the nephron) hence forcing some components of blood out of glomerular capillaries such as water, salt, glucose, urea are passed to Bowmans capsule and are known as glomerular filtrate(contains about 20% of blood plasma) glomerular filtrate is passed from renal capsule to renal tube .Blood cells and plasma proteins are not filtered out because of their large size.
Reabsorption
Tubular reabsorption occurs through three mechanisms
Diffusion-movement of molecules\ions particles from an area of high concentration to an area of low concentration
active transport- a movement of molecules from a low concentrated area to a high concentrated area against a concentration gradient by use of energy
Osmosis-movement of water molecules from of hypotonic concentration to hypertonic concentration through a semi-permeable membrane.
Water and glucose are reabsorbed in the proximal convoluted tubule.There is a high concentration of sodium ions in the filtrate hence it moves from tubular fluids to the proximal convoluted tubule. Other substances that are reabsorbed include glucose, amino acids, lactic acids and bicarbonate ions. 80% of water is reabsorbed through diffusion.
In the loop of Henle, the remaining water, dissolved salts and urea passes through the descending loop of Henle (permeable to water and less permeable to Na, Cl, and urea) this being so it increases the osmotic gradient hence the solutes are reabsorbed by the ascending loop of Henle (permeable to Cl and Na ions impermeable to water)
In the distal convoluted tubule the anti-diuretic hormone makes cells to be more permeable to water hence allows more water to go back to the blood.
Final answer:
The kidneys excrete hypertonic urine to conserve water by reabsorbing solutes from the isotonic plasma, thus increasing the urine's osmolarity. Isotonic solutions have equal solute concentrations in the cells, whereas hypertonic solutions have higher solute concentrations, leading to water exiting the cells.
Explanation:
When the body needs to conserve water, the kidneys excrete hypertonic urine. The terms isotonic and hypertonic are relative measures of osmolarity, or solute concentration, of a solution compared to another solution. In an isotonic solution, the extracellular fluid has the same osmolarity as the cell, which means there will be no net movement of water into or out of the cell. A hypertonic solution, conversely, has a higher concentration of solutes compared to another solution, leading to water moving out of the cells into the surrounding fluid.
Plasma is considered an isotonic solution to the body's cells. To convert the isotonic plasma to hypertonic urine, the kidneys must actively reabsorb solutes from the to-be-excreted fluid back into the bloodstream, thus elevating the osmolarity of the urine. This process ensures that water is retained in the body, especially when dehydrated or when the body needs to maintain higher water retention. The kidneys' ability to adjust the osmolarity of urine is fundamental to maintaining homeostasis within the body.
The recent acts of activists intent on destruction of research plots included plants altered by molecular as well as classical genetic techniques. is it possible to distinguish between plants altered by classical genetics and those altered by modern techniques? if it is possible how is it done?
Yes, it is possible to distinguish between plants altered by classical genetics and those altered by modern techniques by analyzing specific markers and using DNA analysis.
Explanation:
Yes, it is possible to distinguish between plants altered by classical genetics and those altered by modern techniques. One way to do this is by analyzing the presence of specific markers that are associated with each method. For example, classical genetic techniques often result in random insertions or deletions in the genome, which can be identified through DNA sequencing. On the other hand, modern techniques such as genetic engineering involve the precise insertion of specific genes into the plant's genome, which can also be detected through DNA analysis. Scientists can use various molecular biology techniques to analyze the DNA of plants and determine whether they have been altered using classical or modern methods.
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How many crickets will a lizard need to consume if: There are 150 dietary calories in 100 grams of cricket. Crickets weigh 1.0 grams each. It takes 0.5 dietary calories for the lizard to do one pushup. The lizard spends 60 minutes a day doing pushups The lizard does these pushups every day for 30 days during the breeding season The lizard does push-ups at a rate of 10 push ups/ 30 seconds.
4500
6750
9000
12000
Aphotic zones can be found in____.
A) rivers
B) oceans
C) reservoirs
D) aquifers
Its found in oceans if your doing gradpoint
The correct answer is B. Oceans.
Explanation
The aphotic zone is a set of zones characterized by the impossibility of developing photosynthetic processes since less than 1% of sunlight penetrates them. These areas are mainly found in the oceans, approximately from 200 to 4,000 m and the temperature, because in the areas with greater depth, sonar light does not penetrate with the same intensity as in the continental crust. Despite the absence of sonar light, these areas are habitats for species that adapted to these dark conditions. So, the correct answer is B. Oceans.
When energy is used, ATP molecules convert to ADP molecules. This process is called _____. dephosphorylation phosphorylation oxidation diffusion
Answer:
B. Phosphorylation
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A young man presents reporting diarrhea, fecal urgency, and weight loss. his stool is light-coloured and malodorous, and it tends to float and be difficult to flush. he has also noted tender, red bumps on his shins and reports pain and stiffness in his elbows and knees. sigmoidoscopy reveals discontinuous, granulomatous lesions; no blood is detected in his stool. which diagnosis would his care team first suspect?
Which part of a tree always grows down because of gravity?
Which term describes materials that have large and connected pores, such as sand and gravel
The _______ system is the primary system that prevents the risk of various infections.
Even if you live in the middle of North America, the quality of your watershed can affect the quality of the ocean. How can this be?
Evaporation carries materials from your watershed to the ocean.
Materials in your watershed are eventually transported to an ocean.
The amount of water in your watershed will affect ocean evaporation.
Materials in your watershed are not transported to an ocean.
The answer is B) Materials in your watershed are eventually transported to an ocean.
A eukaryotic cell that is involved in synthesizing large amounts of protein might be expected to have
A eukaryotic cell that synthesizes large amounts of protein is expected to have a significant number of ribosomes and a well-developed endoplasmic reticulum and Golgi apparatus, as well as numerous mitochondria for energy.
A eukaryotic cell that is involved in synthesizing large amounts of protein might be expected to have numerous ribosomes, a well-developed endoplasmic reticulum (ER), particularly the rough ER where ribosomes are attached for protein synthesis, and a sizeable Golgi apparatus for modifying, sorting, and packaging the proteins.
Proteins are critical to a cell's functions, and ribosomes are the macromolecular machines that synthesize proteins. The rough ER is involved in the production of proteins destined for insertion into the cell membrane, secretion, or use in lysosomes. The smooth ER is associated with lipid synthesis and detoxification processes. After synthesis, proteins are transferred to the Golgi apparatus, which further modifies them and directs them to their final destinations.
In addition to ER and Golgi, you would expect such a cell to have significant numbers of mitochondria for providing the necessary energy (ATP) required for the protein synthesis process.
The third body, the apollo spacecraft, is assumed to have