The Fugate family, also known as the "Blue People of Kentucky" have a condition known as methemoglobinemia which prevents hemoglobin from carrying oxygen and makes it difficult for unaffected hemoglobin to release oxygen to body tissues. These individuals had a blue complexion, but were otherwise healthy, with many living into their 80's or 90's. These individuals generally have methemoglobin levels of 10-20% of total hemoglobin. How does genetic drift account for the consistency of this level of methemoglobin?

Answers

Answer 1

The genetic drift account for the consistency of this level of methemoglobin as these individuals generally have methemoglobin levels of 10-20% of total hemoglobin.

What do you mean by Methemoglobin?

Methemoglobin is a form of hemoglobin that has been oxidized, changing its heme iron configuration from the ferrous (Fe2+) to the ferric (Fe3+) state. Unlike normal hemoglobin, methemoglobin does not bind oxygen.

Methemoglobinemia can result from either congenital or acquired processes. Congenital forms of methemoglobinemia are due to autosomal recessive defects in the enzyme cytochrome b5 reductase.

Methemoglobin does not bind oxygen, thus effectively leading to a functional anemia. In addition, methemoglobin causes a leftward shift of the oxygen-hemoglobin dissociation curve.

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Answer 2

Final answer:

The consistency of methemoglobin levels in the Fugate family of Kentucky can be explained by genetic drift, a random process that can fix certain alleles in a small, isolated population.

Explanation:

The Fugate family of Kentucky, known for their blue skin due to methemoglobinemia, presents a case where genetic drift could explain the high consistency of methemoglobin levels.

Methemoglobinemia occurs when hemoglobin, which should normally be in the ferrous (Fe²⁺) form, is oxidized to the ferric (Fe³⁺) form, limiting its capacity to carry oxygen.

In the Fugates' isolated population, certain genetic variants, including those affecting methemoglobin levels, could have increased in frequency through genetic drift. This is a random process where allele frequencies within a small population change due to chance events.

Thus, a homogenous environment where the allele for methemoglobinemia is present and no significant selective advantage or disadvantage is attached to it could lead to stable levels of methemoglobin across the population due to genetic drift.

This process is distinct from balancing selection, such as the situation with the sickle cell trait where heterozygotes have a selective advantage in malaria-endemic regions, showing the complexity of genetic inheritance and its interaction with the environment.

Unlike sickle cell trait, no apparent selective advantage is associated with higher levels of methemoglobin, but the closed nature of the gene pool in the Fugate family likely led to the perpetuation and stability of these levels through genetic drift.


Related Questions

What organism eats algae,and another one that eats plants and can be combined in a food chain? Thanks

Answers

Fish? Some fish eat algae and algae are plants

In the 1990s, scientists showed that Archaea and Bacteria are very different groups of organisms. How did this impact the classification system of organisms?
The levels of classification decreased.
The levels of classification increased.
The trinomial nomenclature was introduced.
The binomial nomenclature was introduced.

Answers

The answer is B. The level of classification increases. In 1950 scientists grouped all living things into five kingdoms which include animals, plants, bacteria, fungi and protista. It was untill 1990 that the scientist realized that bacteria and archaea have different distinct characteristics.
Its B hope this helps =)

you notice a sign in a parking structure that says "Warning: This area contains chemicals known to the state of California to cause cancer and birth defects or other reproductive harm". How can these harmful chemicals affect your DNA?

Answers

They can enter your blood stream (via breathing/ingesting) and once in your bloodstream they can enter cells and mutate your dna, which can cause cancer/birth defects/ reproductive harm

Answer:

High-dose chemicals can damage DNA causing genotoxicity, which is defined as damage to DNA or genes. And this can be aggravated since many chemicals have had little toxicological evaluation.

Explanation:

The cancers are caused by mutations in the DNA throughout the life of a person, in such a way that obeying the causative factors, in this case the chemicals, they leave a mutational pattern in the genome of each tumor. There is an interesting biomarker called TGx-DDI, which is based on some genes that are expressed in a cell subjected to the stress produced by the chemical compound. These genes reflect the way in which different pathways can provide information on how cells respond to the chemical.

What are the 3 types of fronts?
Cold, warm, and what?

Answers

There are cold fronts, warm fronts, stationary fronts, and occluded fronts.

how does the cell membrane help maintain homeostasis for the cell?

a. it helps the cell move

b. it regulates the temperature of the cell

c. it controls the growth of the cell

d. it controls what comes in and out of the cell

Answers

I feel like its A because cells cell can homoeostasis by regulating the movement of substances so it would help move the cell.

Hope this helped!

The correct answer is D

I remember learning this

Hope this helps
~Jordan~

In a forest ecosystem including rabbits, wolfs, foxes, and plants, what are two possible reasons the rabbit population might decline?

Answers

One reason could be that there are a high number of predators killing rabbits in large quantities. Another is there may not be enough vegetation for the rabbits. They may also have a different animal competing for the same kinds of plants they eat. 

Answer: There are too Many predators for the rabbits to hide from and The Food supply can decline over time, leading to less food for the remaining rabbits

ticks feed on deer blood to the deers that detriment

Answers

This is known as parasitism. 
In biology, parasitism is a relationship between species, where one organism, the parasite, lives on or in another organism, the host, causing it some harm, and is adapted structurally to this way of life.
Final answer:

True. Ticks are parasitic organisms that feed on the blood of hosts including deer. These ticks can spread pathogens between hosts, potentially causing diseases like Lyme disease. A tick infestation may also affect a deer's overall health.

Explanation:

It seems the student is asking about the impact of ticks feeding on the blood of deer, which falls under the Biology subject, specifically related to parasitism. Ticks are parasites that survive by feeding on the blood of a host.

Deer are common hosts for several types of ticks. When a tick feeds on a deer's blood, the tick might ingest any pathogens in the deer's blood. As ticks continue feeding and switching hosts, they may spread these pathogens to other organisms, including humans. This can lead to diseases such as Lyme disease, amongst others.

Over time, tick infestations can also lead to adverse effects on the deer's health, such as reduced body weight and secondary infections from tick bites.

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The complete question is:

True/False:

ticks feed on deer blood to the deers that detriment

What are the short and long term effects of ocean pollution?

Answers

Long term- can effect reproduction ,system failure and death to marine life
Short term-a chemical that touches the water can it can effect wild life or residents
around it

why is it important for an organism to have the correct number of chromosomes

Answers

It can result in mutations or an inability to procreate. For an example, people with down syndrome have one extra chromosome on chromosome 13.
Multicellular organisms require cell division for growth and repair. All of the new cells must have the same number of chromosomes as the original cell.

Following a car accident, a person is able to walk, but she is not able to move her arms. This person most likely severed
a lumbar nerve
a coccygeal nerve
a cervical nerve
a sacral nerve

Answers

she may have severed a cervical nerves
id say the cervical nerve

What is the independent variable and dependent variable in a Cartesian diver?

Answers

Final answer:

In the Cartesian diver experiment, the independent variable could be the pressure applied to the system, and the dependent variable is the depth at which the diver sinks or floats. Pressure is plotted on the x-axis and diver depth on the y-axis in a graph. The y-intercept is the depth at which the diver is when no pressure is applied, while the slope shows how depth varies with pressure.

Explanation:

In a Cartesian diver experiment, the independent variable is the variable that you control or manipulate. This could be the amount of pressure applied to the closed system in which the diver is located. The dependent variable is the result of that manipulation, which in this case could be the depth at which the diver sinks or floats.

For example, if you squeeze the bottle containing the Cartesian diver, you are increasing the pressure; this is your independent variable. The response to this, the depth at which the diver moves, is the dependent variable because it depends on the pressure applied. In a graph depicting this relationship, the applied pressure would be plotted on the x-axis (horizontal), and the diver's depth would be plotted on the y-axis (vertical).

The y-intercept in a graph represents the value of the dependent variable when the independent variable is zero. If we consider a straight-line graph formula y = mx + b, where m is the slope, and b is the y-intercept, the slope indicates how much the dependent variable changes for a unit change in the independent variable.

Which element in southeast desert ecoystembl is abiotic

Answers

Abiotic being non-living or sterile could cover a lot of elements in a desert ecosystem. Rocks, water, sand and such.

Hope this helps!

-Payshence xoxo

Identify the fungus type pictured below.

Answers

That would be ascomycota or sac fungi. Sac fungi are characteristically known for producing ascus. This is a sac-like structure that contains haploid spores called ascospores. Some examples of sac fungi are yeast, truffles, morels and dead man's fingers. 
It is sac fungi, I'm 99 percent sure of it. Have a great day. :)

how would the body wave affected if red blood cells have low levels of hemoglobin

Answers

You could be considered to have an ameia disease. There are many different types. One can help malaria grow called hemmoragic anemia.

Hope this helps!! ;))
Have a grat day!! <3

In an ecosystem, a wide range of organisms coexist. In a pond ecosystem, one can find amoebae, bacteria, green algae, and fish. Which of the following is the best conclusion one can make regarding the genetic diversity of these organisms? Green algae will have the greatest genetic diversity because they are photosynthetic and do not depend on other organisms to survive. Fish will have the greatest genetic diversity because they receive genetic material from a male and female source. Bacteria will have the greatest genetic diversity because their high reproductive rate ensures that some will survive. Amoebae will have the greatest genetic diversity because their genetic makeup allows them to survive in many environments.

Answers

Answer:

The correct answer would be "Fish will have the greatest genetic diversity because they receive genetic material from a male and female source".

Genetic diversity is defined as the variation in the total amount of genetic information among the individual of the population.

In sexually reproducing population, genetic diversity is present in high amount as compared to asexually reproducing population.

It is because of two reasons:

The genetic make of an individual is determined by 2 parents (father and mother).The event of crossing over takes place during formation of gametes.

Together, they lead to the development of new combinations of alleles in an offspring which is different from both the parents.

Thus, fish would have the highest genetic diversity in their population.

Answer:

Fish will have the greatest genetic diversity because they receive genetic material from a male and female source

Explanation:

what are pheromones?
1. mating behaviors
2. changes in appearance
3 . chemical signals
4. patterns of behavior

Answers

3. chemical signals!

hope that helped :)

Chemical signals - natures love potion ;)

Which two elements primarly make up a nebula?

A) hydrogen and oxygen
B) hydrogen and heilium
C) heilum and oxygen
D) carbon and oxygen

Answers

B is the answer hope this helps
the answer is  b hydrogen and helium 

A farmer has a herd of cattle with an average weight of 1,000 pounds. He breeds a group of his heaviest cattle, which have an average weight of 1,800 pounds. The weight of each offspring is listed below. Offspring 1: 1,648 pounds Offspring 2: 1,640 pounds Offspring 3: 1,718 pounds Offspring 4: 1,794 pounds What’s the average weight of the offspring? The average weight of the offspring is pounds.

Answers

the answer is 1700 pounds

Answer:

The average weight would be 1700 pounds.

Explanation:

Given,

Weight of,

Offspring 1 = 1,648 pounds,

Offspring 2 = 1,640 pounds,

Offspring 3 = 1,718 pounds,

Offspring 4 = 1,794 pounds

Since,

[tex]\text{Average}=\frac{\text{Sum of all observations}}{\text{Number of the observations}}[/tex]

Hence, the average weight of the offspring

[tex]=\frac{1648+1640+1718+1794}{4}[/tex]

[tex]=\frac{6800}{4}[/tex]

[tex]=1700\text{ pounds}[/tex]

TCS foods must be time and temperature controlled

Check all that apply

When throwing food out

Being held/displayed for sale

While thawing

When cooking

during storage

after four hours

at receiving

Answers

Honestly, I thought that TCS was TSC as in Tractor Supply Company. And I was like uhh what? Why does TSC sell food?
Final answer:

TCS foods must be time and temperature controlled during cooking, storage, and after four hours.

Explanation:

TCS foods stands for 'Time/Temperature Control for Safety' foods. These are foods that require specific temperature control to prevent the growth of harmful bacteria and ensure food safety. In the given options, the correct choices for when TCS foods must be time and temperature controlled include:

When cooking: This is important to ensure that the food reaches the proper internal temperature to kill any bacteria present.During storage: TCS foods need to be stored at the correct temperature to prevent bacteria growth. This includes refrigeration for perishable items.After four hours: If TCS foods are left at room temperature for more than four hours, bacteria can multiply to unsafe levels. After this time, they should be discarded to ensure food safety.

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How would the jellyfish population be affected if sea turtles were removed?

Answers

The population of jelly fish would take over, because sea turtles eat them.
Based on a sea turtles diet I would say the jellyfish population would increase. Probably not very rapidly tho, this is because sea turtles diets also consist of other things such as sea grass and algae.

Hope this help!

Arrange the steps of energy production in the correct order.
1 consumption of food
2 cellular respiration in mitochondria
3 breakdown of starch into glucose
4 absorption of glucose molecules
5 creation of ATP

Answers

Here are the correct steps involved in energy production: 

Step 1 - Consumption of food
Step 2 - breakdown of starch into glucose
Step 3 - absorption of glucose molecules
Step 4 -cellular respiration in mitochondria
Step 5 - creation of ATP

ATP is the end-product of aerobic respiration and this occurs in living organisms as soon as they have begun metabolizing the food that they have consumed.

The correct order of energy production includes consumption of food→ Breakdown of starch into glucose → Absorption of glucose molecules → Cellular respiration in mitochondria → Creation of ATP (Energy). ATP is the form of energy in the cell.

What is Energy production?

Energy is produced from the food we consume. Energy is derived from the catabolism of food particles we eat. The food consumed is broken into glucose, this glucose under cellular respiration. Aerobic respiration is the process which includes oxidation of glucose through glycolysis, Citric acid cycle, and Oxidative phosphorylation to produce 36 to 38 molecules of ATP.

The correct order of steps involved in the production of energy include:

Step 1 - Consumption of food

Step 2 - breakdown of starch into glucose

Step 3 - absorption of glucose molecules

Step 4 -cellular respiration in mitochondria

Step 5 - creation of ATP

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what does the muscular system do for your body

Answers

Answer:

It permits movement of the body, maintains posture and circulates blood throughout the body

Explanation:

What are the four components necessary for a plant to perform photosynthesis?

a.chloroplasts, sunlight, carbon dioxide, and water
b. ribosomes, seasons, carbon dioxide, and dew
c.ribosomes, sunlight, oxygen, and water
d.

Answers

the answer is A. I don't believe ribosomes really have anything nothing to do with photosynthesis
a chloroplasts, sunlight, carbon dioxide and water

what did marie and pierre curie discover about radioactivity

Answers

They discovered the elements radium and polonium

Answer:

the elements radium and polonium

Explanation:

Ursus is the___ and maritimus is the ___

Answers

Ursus is the genus and maritimus is the species

Answer:

1.genus

2.species

Explanation:

100% on edg

Which diagram shows the pathway of energy through an ecosystem?

A. producer → carnivore → herbivore

B. producer → herbivore → carnivore

C. herbivore → producer → carnivore

D. carnivore → herbivore → producer

2. Which term names an environmental change that occurs very quickly?

A. succession

B. deforestation

C. global warming

D. regrowth after volcanic eruption

Answers

Question 1:
The correct answer should be the one that shows the producer first, (->) followed by the herbivore, (->) with the carnivore last.
Producers are organisms that harvest their own 'food' using things like the sunlight and water. Examples of producers are grass and other vegetation.

[tex]Producer [/tex]
The herbivore, or an organism that consumes only vegetation and/or algae, consumes the producer.

[tex]Producer [/tex] ⇒ [tex]Herbivore [/tex]
The carnivore consumes meat, or other animals such as the herbivore. It's the last. 

[tex]Producer [/tex] ⇒ [tex]Herbivore[/tex] ⇒ [tex]Carnivore[/tex]
Therefore the answer is B
____________________________________________________________
Question 2:
 I'm pretty sure that succession as well as regrowth after volcanic eruption (Just look at Mount St. Helens. After 30-35 years after the eruption, nature is still recovering) happens over time/slowly. I would say global warming [C](?) would be the answer. 

Producer → herbivore → carnivore is the pathway of energy through an ecosystem.

Global warming is the term of an environmental change that occurs very quickly.

Pathway of enegry through an ecosystem

The producer feeds on plants and make their own food. Herbivore feeds on producer and carnivore feeds on herbivores. Global warming is responsible of climate change in the whole world. This global warming is responsible of melting of glaciers due to increase of temperature.

So we can conclude that option B and C are the correct answers.

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the illustration shown is an ovum, female sex cell. a mutation in this cell may be passed to the woman's offspring during

Answers

Would it be fertilization? That’s when the sperm fertilizes the egg.

The illustration shown is an ovum, a female sex cell. A mutation in this cell may be passed to the woman's offspring during D sexual reproduction.

A mutation is a change in the DNA sequence of a cell. These changes can occur spontaneously or be induced by environmental factors. Mutations in the DNA of sex cells (sperm and ovum) are particularly important because they can be passed to the next generation.

The ovum is one of the two sex cells involved in sexual reproduction. It contains half of the genetic material required to form a new individual. If a mutation occurs in the DNA of an ovum, it alters the genetic information that will be passed to the offspring.

Complete Question:

The illustration shown is an ovum, a female sex cell. A mutation in this cell may be passed to the woman's offspring during A birth. B mitosis. C DNA replication. D sexual reproduction.

What is a Winter Storm Warning?

Answers

A Winter Storm Warning means a winter storm is occurring or is about to occur in the area, usually within 36 hours.
It’s a warning that is sent out to a specific area. It occurs when there is a Winter Storm about to happen.

Hope this helps!

How does the brain generate consciousness?

Answers

By knowing it exists

Final answer:

The brain generates consciousness through complex neural networks responsible for cognitive functions and awareness. Consciousness is considered an evolutionary advantage for efficient navigation and interaction with our environment. It also poses the 'hard problem' of understanding the emergence of subjective experiences from physical processes.

Explanation:

How Does the Brain Generate Consciousness?

The question of how the brain generates consciousness is a profound one that has intrigued scientists, philosophers, and thinkers for centuries. According to Christof Koch, "consciousness is everything you experience." This includes sensations, emotions, thoughts, and the awareness of these experiences.

Biologically speaking, the human brain is composed of a complex network of neurons that interact with each other to process information. This neurological activity underlies our cognitive abilities such as perception, interpretation, imagination, and memory. Consciousness arises when we are able to be aware of these cognitive processes and can reflect on the experiences - an action called introspection.

From an evolutionary perspective, consciousness developed as an advantageous trait for survival, enabling humans to engage with their environment in more sophisticated ways. For instance, consciousness allows for the planning and execution of complex tasks while unconscious mechanisms handle routine functions, making our brain activities more energy efficient.

However, consciousness also poses the hard problem, which is understanding why and how subjective experiences arise from the physical processes of the brain. Neuroscience reveals that brain activity is associated with our decision-making processes, suggesting that even what we perceive as conscious choices are determined by unconscious neural computations.

One aspect of consciousness is self-reflection – the ability to think about oneself within the larger context of the universe. This self-consciousness is a byproduct of the matter itself, including the atoms in our brains, reaching a level of complexity capable of reflecting upon its own existence.

Overall, an optimal accounting of consciousness needs to not only define it but also explain its origin, purpose, and how it affects our neurobiology. Despite the challenging nature of understanding consciousness, it remains an essential aspect of the human experience and cognition.

Your neighbour cannot understand why her new flowerbed now contains pink flowers. She specifically bought and planted only red and white flowers. Explain which condition in genetics allows this to happen.

Answers

Punnet square. The condition of incomplete dominance allows for this to happen.

The presence of pink flowers in a flowerbed intended to contain only red and white flowers is due to incomplete dominance, where neither the red nor the white allele is completely dominant, resulting in a blend of the parental traits visible in the heterozygous flowers as a pink color.

When your neighbor planted only red and white flowers but now observes pink flowers, the explanation lies in the concept of incomplete dominance in genetics. In incomplete dominance, neither allele is completely dominant over the other, leading to a third phenotype that is a blend of the two parental traits. For instance, if a plant with a homozygous red allele (RR) is crossed with a plant with a homozygous white allele (WW), the heterozygous offspring (RW) will display pink flowers. This reveals a phenotype that is neither red nor white, but a mix of both, resulting in the presence of pink flowers.

With incomplete dominance, the red flower allele producing pigment called anthocyanin is not dominant over the white flower allele, and in the heterozygous plants (RW), anthocyanin is present in a reduced amount due to the one white allele. This reduced amount of red pigment on the white background of the flower petals gives the pink appearance. When two heterozygous plants are crossed (RW x RW), the expected offspring would exhibit a genotypic ratio of 1 RR:2 RW:1 WW and a phenotypic ratio of 1 red:2 pink:1 white.

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